Shanahan CS - Search Results

1

Practical Synthesis of 6-Amino-1-hydroxy-2,1-benzoxaborolane: A Key Intermediate of DNDI-6148.

Khairnar PV, Saathoff JM, Cook DW, Hochstetler SR, Pandya U, Robinson SJ, Satam V, Donsbach KO, Gupton BF, Jin LM, Shanahan CS. Khairnar PV, et al. Among authors: shanahan cs. Org Process Res Dev. 2024 Mar 29;28(4):1213-1223. doi: 10.1021/acs.oprd.4c00031. eCollection 2024 Apr 19. Org Process Res Dev. 2024. PMID: 38660377 Free PMC article.

2

Application of Chiral Transfer Reagents to Improve Stereoselectivity and Yields in the Synthesis of the Antituberculosis Drug Bedaquiline.

Robey JMS, Maity S, Aleshire SL, Ghosh A, Yadaw AK, Roy S, Mear SJ, Jamison TF, Sirasani G, Senanayake CH, Stringham RW, Gupton BF, Donsbach KO, Nelson RC, Shanahan CS. Robey JMS, et al. Among authors: shanahan cs. Org Process Res Dev. 2023 Oct 13;27(11):2146-2159. doi: 10.1021/acs.oprd.3c00287. eCollection 2023 Nov 17. Org Process Res Dev. 2023. PMID: 38025988 Free PMC article.

3

Highly Regioselective Protecting-Group-Free Synthesis of the Antimalarial Drug MMV693183.

Khairnar PV, Aleshire SL, Kumar Ongolu R, Jin L, Laidlaw MG, Donsbach KO, Gupton BF, Nelson RC, Shanahan CS. Khairnar PV, et al. Among authors: shanahan cs. Org Process Res Dev. 2023 Dec 9;28(1):273-280. doi: 10.1021/acs.oprd.3c00353. eCollection 2024 Jan 19. Org Process Res Dev. 2023. PMID: 38268773 Free PMC article.

4

Synthetic Process Development of (R)-(+)-1,2-Epoxy-5-hexene: An Important Chiral Building Block.

Guthrie D, Saathoff JM, Sahani RL, Nunes De Souza A, Cook DW, Hochstetler SR, Burns JM, Moazeni-Pourasil RS, Wierzbicki J, Ahmad S, Laidlaw GM, Gupton BF, Shanahan CS, Klumpp DA, Jin L. Guthrie D, et al. Among authors: shanahan cs. Org Process Res Dev. 2024 Aug 1;28(8):3197-3205. doi: 10.1021/acs.oprd.4c00101. eCollection 2024 Aug 16. Org Process Res Dev. 2024. PMID: 39171130 Free PMC article.

5

Diastereoselective addition of monoorganocuprates to a chiral fumarate: reaction development and synthesis of (-)-dihydroprotolichesterinic acid.

Hethcox JC, Shanahan CS, Martin SF. Hethcox JC, et al. Among authors: shanahan cs. Tetrahedron. 2015 Sep 16;71(37):6361-6368. doi: 10.1016/j.tet.2015.05.023. Tetrahedron. 2015. PMID: 26273115 Free PMC article.

6

A survey of enoldiazo nucleophilicity in selective C-C bond forming reactions for the synthesis of natural product-like frameworks.

Liu Y, Liu Y, Shanahan CS, Xu X, Doyle MP. Liu Y, et al. Among authors: shanahan cs. Org Biomol Chem. 2014 Jul 28;12(28):5227-34. doi: 10.1039/c4ob00709c. Epub 2014 Jun 11. Org Biomol Chem. 2014. PMID: 24920324

7

Asymmetric Formal Total Synthesis of the Stemofoline Alkaloids: The Evolution, Development and Application of a Catalytic Dipolar Cycloaddition Cascade.

Shanahan CS, Fang C, Paull DH, Martin SF. Shanahan CS, et al. Tetrahedron. 2013 Sep 9;69(36):7592-7607. doi: 10.1016/j.tet.2013.03.104. Tetrahedron. 2013. PMID: 24072939 Free PMC article.

8

Diazoacetoacetate enones for the synthesis of diverse natural product-like scaffolds.

Shanahan CS, Truong P, Mason SM, Leszczynski JS, Doyle MP. Shanahan CS, et al. Org Lett. 2013 Jul 19;15(14):3642-5. doi: 10.1021/ol4015199. Epub 2013 Jul 5. Org Lett. 2013. PMID: 23829448 Free PMC article.

9

Total synthesis of (-)-dihydroprotolichesterenic acid via diastereoselective conjugate addition to chiral fumarates.

Hethcox JC, Shanahan CS, Martin SF. Hethcox JC, et al. Among authors: shanahan cs. Tetrahedron Lett. 2013 Apr 17;54(16):2074-2076. doi: 10.1016/j.tetlet.2013.02.014. Epub 2013 Feb 11. Tetrahedron Lett. 2013. PMID: 23539490 Free PMC article.

10

Enantioselective formal total syntheses of didehydrostemofoline and isodidehydrostemofoline through a catalytic dipolar cycloaddition cascade.

Fang C, Shanahan CS, Paull DH, Martin SF. Fang C, et al. Among authors: shanahan cs. Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10596-9. doi: 10.1002/anie.201205274. Epub 2012 Sep 17. Angew Chem Int Ed Engl. 2012. PMID: 22987285 Free PMC article.

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