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Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers.
Diepstraten ST, Yuan Y, La Marca JE, Young S, Chang C, Whelan L, Ross AM, Fischer KC, Pomilio G, Morris R, Georgiou A, Litalien V, Brown FC, Roberts AW, Strasser A, Wei AH, Kelly GL. Diepstraten ST, et al. Among authors: la marca je. Cancer Cell. 2024 May 13;42(5):850-868.e9. doi: 10.1016/j.ccell.2024.04.004. Epub 2024 Apr 25. Cancer Cell. 2024. PMID: 38670091 Free article.
BCL-W makes only minor contributions to MYC-driven lymphoma development.
Diepstraten ST, La Marca JE, Chang C, Young S, Strasser A, Kelly GL. Diepstraten ST, et al. Among authors: la marca je. Oncogene. 2023 Sep;42(37):2776-2781. doi: 10.1038/s41388-023-02804-5. Epub 2023 Aug 11. Oncogene. 2023. PMID: 37567974 Free PMC article.
Genome-wide CRISPR screening identifies a role for ARRDC3 in TRP53-mediated responses.
La Marca JE, Aubrey BJ, Yang B, Chang C, Wang Z, Kueh A, Tai L, Wilcox S, Milla L, Heinzel S, Vremec D, Whelan L, König C, Kaloni D, Voss AK, Strasser A, Diepstraten ST, Herold MJ, Kelly GL. La Marca JE, et al. Cell Death Differ. 2024 Feb;31(2):150-158. doi: 10.1038/s41418-023-01249-3. Epub 2023 Dec 14. Cell Death Differ. 2024. PMID: 38097622 Free PMC article.
Mouse models to investigate in situ cell fate decisions induced by p53.
Lieschke E, Thomas AF, Kueh A, Atkin-Smith GK, Baldoni PL, La Marca JE, Young S, Huang AS, Ross AM, Whelan L, Kaloni D, Tai L, Smyth GK, Herold MJ, Hawkins ED, Strasser A, Kelly GL. Lieschke E, et al. Among authors: la marca je. EMBO J. 2024 Oct;43(19):4406-4436. doi: 10.1038/s44318-024-00189-z. Epub 2024 Aug 19. EMBO J. 2024. PMID: 39160273 Free PMC article.
15 results