Rademann J - Search Results

1

Targeted small molecule inhibitors blocking the cytolytic effects of pneumolysin and homologous toxins.

Aziz UBA, Saoud A, Bermudez M, Mieth M, Atef A, Rudolf T, Arkona C, Trenkner T, Böttcher C, Ludwig K, Hoelzemer A, Hocke AC, Wolber G, Rademann J. Aziz UBA, et al. Among authors: rademann j. Nat Commun. 2024 Apr 26;15(1):3537. doi: 10.1038/s41467-024-47741-3. Nat Commun. 2024. PMID: 38670939 Free PMC article.

2

Advanced polymer reagents based on activated reactants and reactive intermediates: powerful novel tools in diversity-oriented synthesis.

Rademann J. Rademann J. Methods Enzymol. 2003;369:366-90. doi: 10.1016/S0076-6879(03)69020-8. Methods Enzymol. 2003. PMID: 14722964 No abstract available.

3

Propargyl amides as irreversible inhibitors of cysteine proteases--a lesson on the biological reactivity of alkynes.

Arkona C, Rademann J. Arkona C, et al. Among authors: rademann j. Angew Chem Int Ed Engl. 2013 Aug 5;52(32):8210-2. doi: 10.1002/anie.201303544. Epub 2013 Jun 21. Angew Chem Int Ed Engl. 2013. PMID: 23794491 No abstract available.

4

Catalytic activation of pre-substrates via dynamic fragment assembly on protein templates.

Burda E, Rademann J. Burda E, et al. Among authors: rademann j. Nat Commun. 2014 Nov 18;5:5170. doi: 10.1038/ncomms6170. Nat Commun. 2014. PMID: 25403979 Free article.

5

Selective inhibitors of the protein tyrosine phosphatase SHP2 block cellular motility and growth of cancer cells in vitro and in vivo.

Grosskopf S, Eckert C, Arkona C, Radetzki S, Böhm K, Heinemann U, Wolber G, von Kries JP, Birchmeier W, Rademann J. Grosskopf S, et al. Among authors: rademann j. ChemMedChem. 2015 May;10(5):815-26. doi: 10.1002/cmdc.201500015. Epub 2015 Apr 15. ChemMedChem. 2015. PMID: 25877780

6

Chemoenzymatic Synthesis of Nonasulfated Tetrahyaluronan with a Paramagnetic Tag for Studying Its Complex with Interleukin-10.

Köhling S, Künze G, Lemmnitzer K, Bermudez M, Wolber G, Schiller J, Huster D, Rademann J. Köhling S, et al. Among authors: rademann j. Chemistry. 2016 Apr 11;22(16):5563-74. doi: 10.1002/chem.201504459. Epub 2016 Feb 25. Chemistry. 2016. PMID: 26918733

7

Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments.

Becker D, Kaczmarska Z, Arkona C, Schulz R, Tauber C, Wolber G, Hilgenfeld R, Coll M, Rademann J. Becker D, et al. Among authors: rademann j. Nat Commun. 2016 Sep 28;7:12761. doi: 10.1038/ncomms12761. Nat Commun. 2016. PMID: 27677239 Free PMC article.

8

Protein-Templated Fragment Ligations-From Molecular Recognition to Drug Discovery.

Jaegle M, Wong EL, Tauber C, Nawrotzky E, Arkona C, Rademann J. Jaegle M, et al. Among authors: rademann j. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7358-7378. doi: 10.1002/anie.201610372. Epub 2017 May 31. Angew Chem Int Ed Engl. 2017. PMID: 28117936 Free PMC article. Review.

9

Phenylthiomethyl Ketone-Based Fragments Show Selective and Irreversible Inhibition of Enteroviral 3C Proteases.

Schulz R, Atef A, Becker D, Gottschalk F, Tauber C, Wagner S, Arkona C, Abdel-Hafez AA, Farag HH, Rademann J, Wolber G. Schulz R, et al. Among authors: rademann j. J Med Chem. 2018 Feb 8;61(3):1218-1230. doi: 10.1021/acs.jmedchem.7b01440. Epub 2018 Jan 27. J Med Chem. 2018. PMID: 29328649

10

Identification of a pyrogallol derivative as a potent and selective human TLR2 antagonist by structure-based virtual screening.

Grabowski M, Murgueitio MS, Bermudez M, Rademann J, Wolber G, Weindl G. Grabowski M, et al. Among authors: rademann j. Biochem Pharmacol. 2018 Aug;154:148-160. doi: 10.1016/j.bcp.2018.04.018. Epub 2018 Apr 22. Biochem Pharmacol. 2018. PMID: 29684378

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