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Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes.
Furukawa S, Haruta M, Arai Y, Honda S, Ohshima J, Sugawara W, Kageyama Y, Higashi Y, Nishida K, Tsunematsu Y, Nakadate H, Ishii M, Kaneko Y. Furukawa S, et al. Among authors: haruta m. Cancer Sci. 2009 Apr;100(4):698-708. doi: 10.1111/j.1349-7006.2009.01102.x. Epub 2009 Feb 24. Cancer Sci. 2009. PMID: 19245437 Free PMC article.
CFC1 is a cancer stemness-regulating factor in neuroblastoma.
Chikaraishi K, Takenobu H, Sugino RP, Mukae K, Akter J, Haruta M, Kurosumi M, Endo TA, Koseki H, Shimojo N, Ohira M, Kamijo T. Chikaraishi K, et al. Among authors: haruta m. Oncotarget. 2017 Jul 11;8(28):45046-45059. doi: 10.18632/oncotarget.18464. Oncotarget. 2017. PMID: 28620148 Free PMC article.
EZH2 regulates neuroblastoma cell differentiation via NTRK1 promoter epigenetic modifications.
Li Z, Takenobu H, Setyawati AN, Akita N, Haruta M, Satoh S, Shinno Y, Chikaraishi K, Mukae K, Akter J, Sugino RP, Nakazawa A, Nakagawara A, Aburatani H, Ohira M, Kamijo T. Li Z, et al. Among authors: haruta m. Oncogene. 2018 May;37(20):2714-2727. doi: 10.1038/s41388-018-0133-3. Epub 2018 Mar 6. Oncogene. 2018. PMID: 29507419 Free PMC article.
Frequent breakpoints of focal deletion and uniparental disomy in 22q11.1 or 11.2 segmental duplication region reveal distinct tumorigenesis in rhabdoid tumor of the kidney.
Haruta M, Arai Y, Okita H, Tanaka Y, Takimoto T, Kamijo T, Oue T, Souzaki R, Taguchi T, Kuwahara Y, Chin M, Nakadate H, Hiyama E, Ishida Y, Koshinaga T, Kaneko Y. Haruta M, et al. Genes Chromosomes Cancer. 2021 Aug;60(8):546-558. doi: 10.1002/gcc.22952. Epub 2021 May 4. Genes Chromosomes Cancer. 2021. PMID: 33896058
281 results