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Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration.
Lee S, Vander Roest AS, Blair CA, Kao K, Bremner SB, Childers MC, Pathak D, Heinrich P, Lee D, Chirikian O, Mohran SE, Roberts B, Smith JE, Jahng JW, Paik DT, Wu JC, Gunawardane RN, Ruppel KM, Mack DL, Pruitt BL, Regnier M, Wu SM, Spudich JA, Bernstein D. Lee S, et al. Among authors: bernstein d. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2318413121. doi: 10.1073/pnas.2318413121. Epub 2024 Apr 29. Proc Natl Acad Sci U S A. 2024. PMID: 38683993 Free PMC article.
Microsystems for biomechanical measurements.
Norman JJ, Mukundan V, Bernstein D, Pruitt BL. Norman JJ, et al. Among authors: bernstein d. Pediatr Res. 2008 May;63(5):576-83. doi: 10.1203/PDR.0b013e31816b2ec4. Pediatr Res. 2008. PMID: 18427304 Review.
In vivo functional and transcriptional profiling of bone marrow stem cells after transplantation into ischemic myocardium.
Sheikh AY, Huber BC, Narsinh KH, Spin JM, van der Bogt K, de Almeida PE, Ransohoff KJ, Kraft DL, Fajardo G, Ardigo D, Ransohoff J, Bernstein D, Fischbein MP, Robbins RC, Wu JC. Sheikh AY, et al. Among authors: bernstein d. Arterioscler Thromb Vasc Biol. 2012 Jan;32(1):92-102. doi: 10.1161/ATVBAHA.111.238618. Epub 2011 Oct 27. Arterioscler Thromb Vasc Biol. 2012. PMID: 22034515 Free PMC article.
Time-dependent evolution of functional vs. remodeling signaling in induced pluripotent stem cell-derived cardiomyocytes and induced maturation with biomechanical stimulation.
Jung G, Fajardo G, Ribeiro AJ, Kooiker KB, Coronado M, Zhao M, Hu DQ, Reddy S, Kodo K, Sriram K, Insel PA, Wu JC, Pruitt BL, Bernstein D. Jung G, et al. Among authors: bernstein d. FASEB J. 2016 Apr;30(4):1464-79. doi: 10.1096/fj.15-280982. Epub 2015 Dec 16. FASEB J. 2016. PMID: 26675706 Free PMC article.
In "early" hiPSC-CMs (less than or equal to d 30), beta2-ARs are a primary source of cAMP/PKA signaling. With longer culture, beta1-AR signaling increases: from 0% of cAMP generation at d 30 to 56.8 6.6% by d 60. ...S., Kooiker, K. B., Coronado, M., Zhao, M., …
In "early" hiPSC-CMs (less than or equal to d 30), beta2-ARs are a primary source of cAMP/PKA signaling. With longer culture, beta1-A …
Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity.
Burridge PW, Li YF, Matsa E, Wu H, Ong SG, Sharma A, Holmström A, Chang AC, Coronado MJ, Ebert AD, Knowles JW, Telli ML, Witteles RM, Blau HM, Bernstein D, Altman RB, Wu JC. Burridge PW, et al. Among authors: bernstein d. Nat Med. 2016 May;22(5):547-56. doi: 10.1038/nm.4087. Epub 2016 Apr 18. Nat Med. 2016. PMID: 27089514 Free PMC article.
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy.
Kodo K, Ong SG, Jahanbani F, Termglinchan V, Hirono K, InanlooRahatloo K, Ebert AD, Shukla P, Abilez OJ, Churko JM, Karakikes I, Jung G, Ichida F, Wu SM, Snyder MP, Bernstein D, Wu JC. Kodo K, et al. Among authors: bernstein d. Nat Cell Biol. 2016 Oct;18(10):1031-42. doi: 10.1038/ncb3411. Epub 2016 Sep 19. Nat Cell Biol. 2016. PMID: 27642787 Free PMC article.
1,918 results