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The factor inhibiting HIF regulates T cell differentiation and anti-tumour efficacy.
Bargiela D, Cunha PP, Veliça P, Krause LCM, Brice M, Barbieri L, Gojkovic M, Foskolou IP, Rundqvist H, Johnson RS. Bargiela D, et al. Among authors: foskolou ip. Front Immunol. 2024 Apr 16;15:1293723. doi: 10.3389/fimmu.2024.1293723. eCollection 2024. Front Immunol. 2024. PMID: 38690263 Free PMC article.
The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function.
Foskolou IP, Cunha PP, Sánchez-López E, Minogue EA, Nicolet BP, Guislain A, Jorgensen C, Kostidis S, Zandhuis ND, Barbieri L, Bargiela D, Nathanael D, Tyrakis PA, Palazon A, Giera M, Wolkers MC, Johnson RS. Foskolou IP, et al. Cell Rep. 2023 Sep 26;42(9):113013. doi: 10.1016/j.celrep.2023.113013. Epub 2023 Aug 24. Cell Rep. 2023. PMID: 37632752 Free article.
Glutarate regulates T cell metabolism and anti-tumour immunity.
Minogue E, Cunha PP, Wadsworth BJ, Grice GL, Sah-Teli SK, Hughes R, Bargiela D, Quaranta A, Zurita J, Antrobus R, Velica P, Barbieri L, Wheelock CE, Koivunen P, Nathan JA, Foskolou IP, Johnson RS. Minogue E, et al. Among authors: foskolou ip. Nat Metab. 2023 Oct;5(10):1747-1764. doi: 10.1038/s42255-023-00855-2. Epub 2023 Aug 21. Nat Metab. 2023. PMID: 37605057 Free PMC article.
2-hydroxyglutarate rides the cancer-immunity cycle.
Foskolou IP, Bunse L, Van den Bossche J. Foskolou IP, et al. Curr Opin Biotechnol. 2023 Oct;83:102976. doi: 10.1016/j.copbio.2023.102976. Epub 2023 Jul 27. Curr Opin Biotechnol. 2023. PMID: 37515937 Free article. Review.
Lactate exposure shapes the metabolic and transcriptomic profile of CD8+ T cells.
Barbieri L, Veliça P, Gameiro PA, Cunha PP, Foskolou IP, Rullman E, Bargiela D, Johnson RS, Rundqvist H. Barbieri L, et al. Among authors: foskolou ip. Front Immunol. 2023 Feb 27;14:1101433. doi: 10.3389/fimmu.2023.1101433. eCollection 2023. Front Immunol. 2023. PMID: 36923405 Free PMC article.
Vitamin B6 Metabolism Determines T Cell Anti-Tumor Responses.
Bargiela D, Cunha PP, Veliça P, Foskolou IP, Barbieri L, Rundqvist H, Johnson RS. Bargiela D, et al. Among authors: foskolou ip. Front Immunol. 2022 Feb 17;13:837669. doi: 10.3389/fimmu.2022.837669. eCollection 2022. Front Immunol. 2022. PMID: 35251031 Free PMC article.
Hypoxia-induced SETX links replication stress with the unfolded protein response.
Ramachandran S, Ma TS, Griffin J, Ng N, Foskolou IP, Hwang MS, Victori P, Cheng WC, Buffa FM, Leszczynska KB, El-Khamisy SF, Gromak N, Hammond EM. Ramachandran S, et al. Among authors: foskolou ip. Nat Commun. 2021 Jun 17;12(1):3686. doi: 10.1038/s41467-021-24066-z. Nat Commun. 2021. PMID: 34140498 Free PMC article.
Oxygen regulation of TET enzymes.
Matuleviciute R, Cunha PP, Johnson RS, Foskolou IP. Matuleviciute R, et al. Among authors: foskolou ip. FEBS J. 2021 Dec;288(24):7143-7161. doi: 10.1111/febs.15695. Epub 2021 Jan 29. FEBS J. 2021. PMID: 33410283 Free article. Review.
20 results