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242 results

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Page 1
BET inhibition decreases HMGCS2 and sensitizes resistant pancreatic tumors to gemcitabine.
Miller AL, Fehling SC, Vance RB, Chen D, Brown EJ, Hossain MI, Heard EO, Andrabi SA, Wang H, Yang ES, Buchsbaum DJ, van Waardenburg RCAM, Bellis SL, Yoon KJ. Miller AL, et al. Among authors: buchsbaum dj. Cancer Lett. 2024 Jun 28;592:216919. doi: 10.1016/j.canlet.2024.216919. Epub 2024 May 3. Cancer Lett. 2024. PMID: 38704133
A Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth and Induces Antitumor Immunity in Gastrointestinal Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith FT, Berry K, Holmes TW, Wang J, Huang CH, Ward A, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponeko V, Abdelkarim H, Boyd MR, Gorman G, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. Among authors: buchsbaum dj. Cancer Res. 2024 Dec 19. doi: 10.1158/0008-5472.CAN-24-0323. Online ahead of print. Cancer Res. 2024. PMID: 39700396
ADT-1004: A First-in-Class, Orally Bioavailable Selective pan-RAS Inhibitor for Pancreatic Ductal Adenocarcinoma.
Reddy Bandi DS, Nagaraju GP, Sarvesh S, Carstens JL, Foote JB, Graff EC, Fang YD, Keeton AB, Chen X, Berry KL, Bae S, Akce M, Gorman G, Yoon KJ, Manne U, Boyd MR, Buchsbaum DJ, Azmi AS, Maxuitenko YY, Piazza GA, El-Rayes BF. Reddy Bandi DS, et al. Among authors: buchsbaum dj. bioRxiv [Preprint]. 2024 Oct 8:2024.10.04.616725. doi: 10.1101/2024.10.04.616725. bioRxiv. 2024. PMID: 39416034 Free PMC article. Preprint.
A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer.
Foote JB, Mattox TE, Keeton AB, Chen X, Smith F, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Mitra AK, Ramirez-Alcantara V, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Nagaraju GP, Bandi DSR, Maxuitenko YY, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponenko V, Abdelkarim H, Boyd MR, Gorman GS, Manne U, Bae S, El-Rayes BF, Piazza GA. Foote JB, et al. Among authors: buchsbaum dj. bioRxiv [Preprint]. 2024 Oct 7:2023.05.17.541233. doi: 10.1101/2023.05.17.541233. bioRxiv. 2024. Update in: Cancer Res. 2024 Dec 19. doi: 10.1158/0008-5472.CAN-24-0323 PMID: 38328254 Free PMC article. Updated. Preprint.
ST6GAL1 sialyltransferase promotes acinar to ductal metaplasia and pancreatic cancer progression.
Bhalerao N, Chakraborty A, Marciel MP, Hwang J, Britain CM, Silva AD, Eltoum IE, Jones RB, Alexander KL, Smythies LE, Smith PD, Crossman DK, Crowley MR, Shin B, Harrington LE, Yan Z, Bethea MM, Hunter CS, Klug CA, Buchsbaum DJ, Bellis SL. Bhalerao N, et al. Among authors: buchsbaum dj. JCI Insight. 2023 Oct 9;8(19):e161563. doi: 10.1172/jci.insight.161563. JCI Insight. 2023. PMID: 37643018 Free PMC article.
Editorial: Targeting the Wnt/β-catenin signaling pathway in cancer.
Patergnani S, Buchsbaum DJ, Piazza GA. Patergnani S, et al. Among authors: buchsbaum dj. Front Oncol. 2022 Sep 13;12:1022174. doi: 10.3389/fonc.2022.1022174. eCollection 2022. Front Oncol. 2022. PMID: 36176399 Free PMC article. No abstract available.
Pan-RAS inhibitors: Hitting multiple RAS isozymes with one stone.
Coley AB, Ward A, Keeton AB, Chen X, Maxuitenko Y, Prakash A, Li F, Foote JB, Buchsbaum DJ, Piazza GA. Coley AB, et al. Among authors: buchsbaum dj. Adv Cancer Res. 2022;153:131-168. doi: 10.1016/bs.acr.2021.07.009. Epub 2021 Aug 26. Adv Cancer Res. 2022. PMID: 35101229 Review.
Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS.
Ward AB, Keeton AB, Chen X, Mattox TE, Coley AB, Maxuitenko YY, Buchsbaum DJ, Randall TD, Zhou G, Piazza GA. Ward AB, et al. Among authors: buchsbaum dj. MedComm (2020). 2020 Sep;1(2):121-128. doi: 10.1002/mco2.10. Epub 2020 Jun 25. MedComm (2020). 2020. PMID: 33073260 Free PMC article.
242 results