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Comprehensive Stress Stability Studies Reveal the Prominent Stability of the Liquid-Formulated Biotherapeutic Asymmetric Monovalent Bispecific IgG1 Monoclonal Antibody Format.
Sankaran PK, Poskute R, Dewis L, Watanabe Y, Wong V, Fernandez LP, Shannon R, Wong L, Shrubsall R, Carman L, Holt A, Lepore G, Mishra R, Sewell L, Gothard M, Cheeks M, Lindo V. Sankaran PK, et al. Among authors: poskute r. J Pharm Sci. 2024 Aug;113(8):2101-2113. doi: 10.1016/j.xphs.2024.04.029. Epub 2024 May 3. J Pharm Sci. 2024. PMID: 38705464
Identification and quantification of chain-pairing variants or mispaired species of asymmetric monovalent bispecific IgG1 monoclonal antibody format using reverse-phase polyphenyl chromatography coupled electrospray ionization mass spectrometry.
Poskute R, Sankaran PK, Sewell L, Lepore G, Shrubsall R, Dewis L, Watanabe Y, Wong V, Pascual Fernandez L, Mishra R, Holt A, Sou S, Harris C, Moreno Rodriguez C, Cankorur-Cetinkaya A, Smith J, Lonska N, Powell A, Cui T, Cheeks M, Lindo V. Poskute R, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2024 Apr 15;1237:124085. doi: 10.1016/j.jchromb.2024.124085. Epub 2024 Mar 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2024. PMID: 38513430