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Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment.
Fuller AM, Pruitt HC, Liu Y, Irizarry-Negron VM, Pan H, Song H, DeVine A, Katti RS, Devalaraja S, Ciotti GE, Gonzalez MV, Williams EF, Murazzi I, Ntekoumes D, Skuli N, Hakonarson H, Zabransky DJ, Trevino JG, Weeraratna A, Weber K, Haldar M, Fraietta JA, Gerecht S, Eisinger-Mathason TSK. Fuller AM, et al. Among authors: skuli n. J Clin Invest. 2024 Apr 23;134(11):e167826. doi: 10.1172/JCI167826. J Clin Invest. 2024. PMID: 38652549 Free PMC article.
Nuclear speckles regulate functional programs in cancer.
Alexander KA, Yu R, Skuli N, Coffey NJ, Nguyen S, Faunce CL, Huang H, Dardani IP, Good AL, Lim J, Li CY, Biddle N, Joyce EF, Raj A, Lee D, Keith B, Simon MC, Berger SL. Alexander KA, et al. Among authors: skuli n. Nat Cell Biol. 2025 Jan 2. doi: 10.1038/s41556-024-01570-0. Online ahead of print. Nat Cell Biol. 2025. PMID: 39747580
A mitochondrial surveillance mechanism activated by SRSF2 mutations in hematologic malignancies.
Liu X, Devadiga SA, Stanley RF, Morrow R, Janssen K, Quesnel-Vallières M, Pomp O, Moverley AA, Li C, Skuli N, Carroll MP, Huang J, Wallace DC, Lynch KW, Abdel-Wahab O, Klein PS. Liu X, et al. Among authors: skuli n. bioRxiv [Preprint]. 2024 Apr 23:2023.06.25.546449. doi: 10.1101/2023.06.25.546449. bioRxiv. 2024. Update in: J Clin Invest. 2024 May 7;134(12):e175619. doi: 10.1172/JCI175619 PMID: 38712254 Free PMC article. Updated. Preprint.
Bile Acid Metabolism Mediates Cholesterol Homeostasis and Promotes Tumorigenesis in Clear Cell Renal Cell Carcinoma.
Riscal R, Gardner SM, Coffey NJ, Carens M, Mesaros C, Xu JP, Xue Y, Davis L, Demczyszyn S, Vogt A, Olia A, Finan JM, Godfrey J, Schultz DC, Blair IA, Keith B, Marmorstein R, Skuli N, Simon MC. Riscal R, et al. Among authors: skuli n. Cancer Res. 2024 May 15;84(10):1570-1582. doi: 10.1158/0008-5472.CAN-23-0821. Cancer Res. 2024. PMID: 38417134 Free PMC article.
Humanization with CD34-positive hematopoietic stem cells in NOG-EXL mice results in improved long-term survival and less severe myeloid cell hyperactivation phenotype relative to NSG-SGM3 mice.
Willis E, Verrelle J, Banerjee E, Assenmacher CA, Tarrant JC, Skuli N, Jacobson ML, O'Rouke DM, Binder ZA, Radaelli E. Willis E, et al. Among authors: skuli n. Vet Pathol. 2024 Jul;61(4):664-674. doi: 10.1177/03009858231222216. Epub 2024 Jan 10. Vet Pathol. 2024. PMID: 38197423 Free PMC article.
Nuclear speckles regulate HIF-2α programs and correlate with patient survival in kidney cancer.
Alexander KA, Yu R, Skuli N, Coffey NJ, Nguyen S, Faunce C, Huang H, Dardani IP, Good AL, Lim J, Li C, Biddle N, Joyce EF, Raj A, Lee D, Keith B, Simon MC, Berger SL. Alexander KA, et al. Among authors: skuli n. bioRxiv [Preprint]. 2023 Sep 16:2023.09.14.557228. doi: 10.1101/2023.09.14.557228. bioRxiv. 2023. PMID: 37745397 Free PMC article. Preprint.
65 results