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Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition.
Beauchamp E, Gamma JM, Cromwell CR, Moussa EW, Pain R, Kostiuk MA, Acevedo-Morantes C, Iyer A, Yap M, Vincent KM, Postovit LM, Julien O, Hubbard BP, Mackey JR, Berthiaume LG. Beauchamp E, et al. Among authors: pain r. J Transl Med. 2024 May 7;22(1):431. doi: 10.1186/s12967-024-05150-6. J Transl Med. 2024. PMID: 38715059 Free PMC article.
Zelenirstat Inhibits N-Myristoyltransferases to Disrupt Src Family Kinase Signaling and Oxidative Phosphorylation, Killing Acute Myeloid Leukemia Cells.
Gamma JM, Liu Q, Beauchamp E, Iyer A, Yap MC, Zak Z, Ekstrom C, Pain R, Kostiuk MA, Mackey JR, Brandwein J, Wang JCY, Berthiaume LG. Gamma JM, et al. Among authors: pain r. Mol Cancer Ther. 2025 Jan 2;24(1):69-80. doi: 10.1158/1535-7163.MCT-24-0307. Mol Cancer Ther. 2025. PMID: 39382188 Free PMC article.
Correction for Kulbaba et al. (2019).
Geyer CJ, Kulbaba MW, Sheth SN, Pain RE, Eckhart VM, Shaw RG. Geyer CJ, et al. Among authors: pain re. Evolution. 2022 Dec;76(12):3074. doi: 10.1111/evo.14607. Epub 2022 Sep 6. Evolution. 2022. PMID: 36066095 No abstract available.
Unification at the cost of realism and precision.
Brown RL, Brusse C, Huebner B, Pain R. Brown RL, et al. Among authors: pain r. Behav Brain Sci. 2020 May 28;43:e95. doi: 10.1017/S0140525X19002760. Behav Brain Sci. 2020. PMID: 32460923
188 results