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Page 1
Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways.
Alba-Linares JJ, Pérez RF, Tejedor JR, Bastante-Rodríguez D, Ponce F, Carbonell NG, Zafra RG, Fernández AF, Fraga MF, Lurbe E. Alba-Linares JJ, et al. Among authors: fraga mf. Cardiovasc Diabetol. 2023 Mar 4;22(1):44. doi: 10.1186/s12933-023-01774-y. Cardiovasc Diabetol. 2023. PMID: 36870961 Free PMC article.
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Tejedor JR, Peñarroya A, Gancedo-Verdejo J, Santamarina-Ojeda P, Pérez RF, López-Tamargo S, Díez-Borge A, Alba-Linares JJ, González-Del-Rey N, Urdinguio RG, Mangas C, Roberti A, López V, Morales-Ruiz T, Ariza RR, Roldán-Arjona T, Meijón M, Valledor L, Cañal MJ, Fernández-Martínez D, Fernández-Hevia M, Jiménez-Fonseca P, García-Flórez LJ, Fernández AF, Fraga MF. Tejedor JR, et al. Among authors: fraga mf. Clin Epigenetics. 2023 Aug 24;15(1):133. doi: 10.1186/s13148-023-01546-1. Clin Epigenetics. 2023. PMID: 37612734 Free PMC article.
A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin.
González J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Espinosa-Alcantud M, Fernandez AF, Brown JP, Ausió J, Vazquez BN, Singh PB, Fraga MF, Vaquero A. González J, et al. Among authors: fraga mf. Front Cell Dev Biol. 2023 Nov 9;11:1293122. doi: 10.3389/fcell.2023.1293122. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020886 Free PMC article.
ZEB1 hypermethylation is associated with better prognosis in patients with colon cancer.
Fernandez-De-Los-Reyes I, Gomez-Dorronsoro M, Monreal-Santesteban I, Fernandez-Fernandez A, Fraga M, Azcue P, Alonso L, Fernandez-Marlasca B, Suarez J, Cordoba-Iturriagagoitia A, Guerrero-Setas D. Fernandez-De-Los-Reyes I, et al. Clin Epigenetics. 2023 Dec 13;15(1):193. doi: 10.1186/s13148-023-01605-7. Clin Epigenetics. 2023. PMID: 38093305 Free PMC article.
A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma.
Rey V, Tornín J, Alba-Linares JJ, Robledo C, Murillo D, Rodríguez A, Gallego B, Huergo C, Viera C, Braña A, Astudillo A, Heymann D, Szuhai K, Bovée JVMG, Fernández AF, Fraga MF, Alonso J, Rodríguez R. Rey V, et al. Among authors: fraga mf. EBioMedicine. 2024 Apr;102:105090. doi: 10.1016/j.ebiom.2024.105090. Epub 2024 Mar 27. EBioMedicine. 2024. PMID: 38547578 Free PMC article.
Integration of multi-omics layers empowers precision diagnosis through unveiling pathogenic mechanisms on maple syrup urine disease.
Tejedor JR, Soriano-Sexto A, Beccari L, Castejón-Fernández N, Correcher P, Sainz-Ledo L, Alba-Linares JJ, Urdinguio RG, Ugarte M, Fernández AF, Rodríguez-Pombo P, Fraga MF, Pérez B. Tejedor JR, et al. Among authors: fraga mf. J Inherit Metab Dis. 2024 Dec 10. doi: 10.1002/jimd.12829. Online ahead of print. J Inherit Metab Dis. 2024. PMID: 39659154
Circulating miRNA expression in long-standing type 1 diabetes mellitus.
Morales-Sánchez P, Lambert C, Ares-Blanco J, Suárez-Gutiérrez L, Villa-Fernández E, Garcia AV, García-Villarino M, Tejedor JR, Fraga MF, Torre EM, Pujante P, Delgado E. Morales-Sánchez P, et al. Among authors: fraga mf. Sci Rep. 2023 May 27;13(1):8611. doi: 10.1038/s41598-023-35836-8. Sci Rep. 2023. PMID: 37244952 Free PMC article.
Metformin and Glucose Concentration as Limiting Factors in Retinal Pigment Epithelial Cell Viability and Proliferation.
Villa-Fernández E, García AV, Fernández-Fernández A, García-Villarino M, Ares-Blanco J, Pujante P, González-Vidal T, Fraga MF, Torre EM, Delgado E, Lambert C. Villa-Fernández E, et al. Among authors: fraga mf. Int J Mol Sci. 2024 Feb 24;25(5):2637. doi: 10.3390/ijms25052637. Int J Mol Sci. 2024. PMID: 38473884 Free PMC article.
255 results