Blouse G - Search Results

1

Correlation of antigen expression with epigenetic modifications after rAAV delivery of a human factor IX variant in mice and rhesus macaques.

Pekrun K, Stephens CJ, Gonzalez-Sandoval A, Goswami A, Zhang F, Tarantal AF, Blouse G, Kay MA. Pekrun K, et al. Among authors: blouse g. Mol Ther. 2024 Jul 3;32(7):2064-2079. doi: 10.1016/j.ymthe.2024.05.005. Epub 2024 May 7. Mol Ther. 2024. PMID: 38715361

2

Gene therapy for hemophilia B using CB 2679d-GT: a novel factor IX variant with higher potency than factor IX Padua.

Nair N, De Wolf D, Nguyen PA, Pham QH, Samara-Kuko E, Landau J, Blouse GE, Chuah MK, VandenDriessche T. Nair N, et al. Among authors: blouse ge. Blood. 2021 May 27;137(21):2902-2906. doi: 10.1182/blood.2020006005. Blood. 2021. PMID: 33735915 Free PMC article.

3

Model-Informed Support of Dose Selection for Prophylactic Treatment with Dalcinonacog Alfa in Adult and Paediatric Hemophilia B Patients.

Faraj A, Le Moan N, Gorina E, Blouse GE, Knudsen T, Simonsson USH. Faraj A, et al. Among authors: blouse ge. Adv Ther. 2023 Sep;40(9):3739-3750. doi: 10.1007/s12325-023-02570-6. Epub 2023 Jun 21. Adv Ther. 2023. PMID: 37341915 Free PMC article.

4

Phase III dose selection of marzeptacog alfa (activated) informed by population pharmacokinetic modeling: A novel hemostatic drug.

Faraj A, Knudsen T, Desai S, Neuman L, Blouse GE, Simonsson USH. Faraj A, et al. Among authors: blouse ge. CPT Pharmacometrics Syst Pharmacol. 2022 Dec;11(12):1628-1637. doi: 10.1002/psp4.12872. Epub 2022 Oct 18. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 36191169 Free PMC article.

5

Model-informed pediatric dose selection of marzeptacog alfa (activated): An exposure matching strategy.

Faraj A, van Wijk RC, Neuman L, Desai S, Blouse GE, Knudsen T, Simonsson USH. Faraj A, et al. Among authors: blouse ge. CPT Pharmacometrics Syst Pharmacol. 2023 Jul;12(7):977-987. doi: 10.1002/psp4.12967. Epub 2023 May 2. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 37042339 Free PMC article. Clinical Trial.

6

Subcutaneous Marzeptacog Alfa (Activated) for On-Demand Treatment of Bleeding Events in Subjects With Hemophilia A or B With Inhibitors.

Faraj A, Nyberg J, Blouse GE, Knudsen T, Simonsson USH. Faraj A, et al. Among authors: blouse ge. Clin Pharmacol Ther. 2024 Mar;115(3):498-505. doi: 10.1002/cpt.3172. Epub 2024 Jan 16. Clin Pharmacol Ther. 2024. PMID: 38173172

7

Factor VIII with a 237 amino acid B-domain has an extended half-life in F8-knockout mice.

Bloem E, Karpf DM, Nørby PL, Johansen PB, Loftager M, Rahbek-Nielsen H, Petersen HH, Blouse GE, Thim L, Kjalke M, Bolt G. Bloem E, et al. Among authors: blouse ge. J Thromb Haemost. 2019 Feb;17(2):350-360. doi: 10.1111/jth.14355. Epub 2019 Jan 25. J Thromb Haemost. 2019. PMID: 30525289 Free article.

8

Releasing the brakes in coagulation Factor IXa by co-operative maturation of the substrate-binding site.

Kristensen LH, Olsen OH, Blouse GE, Brandstetter H. Kristensen LH, et al. Among authors: blouse ge. Biochem J. 2016 Aug 1;473(15):2395-411. doi: 10.1042/BCJ20160336. Epub 2016 May 19. Biochem J. 2016. PMID: 27208168

9

Targeting the autolysis loop of urokinase-type plasminogen activator with conformation-specific monoclonal antibodies.

Botkjaer KA, Fogh S, Bekes EC, Chen Z, Blouse GE, Jensen JM, Mortensen KK, Huang M, Deryugina E, Quigley JP, Declerck PJ, Andreasen PA. Botkjaer KA, et al. Among authors: blouse ge. Biochem J. 2011 Aug 15;438(1):39-51. doi: 10.1042/BJ20110129. Biochem J. 2011. PMID: 21635223 Free PMC article.

10

Nonproteolytic induction of catalytic activity into the single-chain form of urokinase-type plasminogen activator by dipeptides.

Bøtkjaer KA, Byszuk AA, Andersen LM, Christensen A, Andreasen PA, Blouse GE. Bøtkjaer KA, et al. Among authors: blouse ge. Biochemistry. 2009 Oct 13;48(40):9606-17. doi: 10.1021/bi900510f. Biochemistry. 2009. PMID: 19705874

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