Scherlach K - Search Results

1

The unusual mode of action of the polyketide glycoside antibiotic cervimycin C.

Hoffmann A, Steffens U, Maček B, Franz-Wachtel M, Nieselt K, Harbig TA, Scherlach K, Hertweck C, Sahl H-G, Bierbaum G. Hoffmann A, et al. Among authors: scherlach k. mSphere. 2024 May 29;9(5):e0076423. doi: 10.1128/msphere.00764-23. Epub 2024 May 9. mSphere. 2024. PMID: 38722162 Free PMC article.

2

Antimitotic rhizoxin derivatives from a cultured bacterial endosymbiont of the rice pathogenic fungus Rhizopus microsporus.

Scherlach K, Partida-Martinez LP, Dahse HM, Hertweck C. Scherlach K, et al. J Am Chem Soc. 2006 Sep 6;128(35):11529-36. doi: 10.1021/ja062953o. J Am Chem Soc. 2006. PMID: 16939276

3

Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining.

Scherlach K, Hertweck C. Scherlach K, et al. Org Biomol Chem. 2006 Sep 21;4(18):3517-20. doi: 10.1039/b607011f. Epub 2006 Aug 10. Org Biomol Chem. 2006. PMID: 17036148

4

The boat-shaped polyketide resistoflavin results from re-facial central hydroxylation of the discoid metabolite resistomycin.

Ishida K, Maksimenka K, Fritzsche K, Scherlach K, Bringmann G, Hertweck C. Ishida K, et al. Among authors: scherlach k. J Am Chem Soc. 2006 Nov 15;128(45):14619-24. doi: 10.1021/ja064550u. J Am Chem Soc. 2006. PMID: 17090047

5

Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans.

Bergmann S, Schümann J, Scherlach K, Lange C, Brakhage AA, Hertweck C. Bergmann S, et al. Among authors: scherlach k. Nat Chem Biol. 2007 Apr;3(4):213-7. doi: 10.1038/nchembio869. Epub 2007 Mar 18. Nat Chem Biol. 2007. PMID: 17369821

6

A cryptic PKS-NRPS gene locus in the plant commensal Pseudomonas fluorescens Pf-5 codes for the biosynthesis of an antimitotic rhizoxin complex.

Brendel N, Partida-Martinez LP, Scherlach K, Hertweck C. Brendel N, et al. Among authors: scherlach k. Org Biomol Chem. 2007 Jul 21;5(14):2211-3. doi: 10.1039/b707762a. Epub 2007 Jun 18. Org Biomol Chem. 2007. PMID: 17609750

7

Activation of fungal silent gene clusters: a new avenue to drug discovery.

Brakhage AA, Schuemann J, Bergmann S, Scherlach K, Schroeckh V, Hertweck C. Brakhage AA, et al. Among authors: scherlach k. Prog Drug Res. 2008;66:1, 3-12. doi: 10.1007/978-3-7643-8595-8_1. Prog Drug Res. 2008. PMID: 18416304 Review.

8

Polyketide-chain branching by an enzymatic Michael addition.

Kusebauch B, Busch B, Scherlach K, Roth M, Hertweck C. Kusebauch B, et al. Among authors: scherlach k. Angew Chem Int Ed Engl. 2009;48(27):5001-4. doi: 10.1002/anie.200900277. Angew Chem Int Ed Engl. 2009. PMID: 19266509

9

Global distribution and evolution of a toxinogenic Burkholderia-Rhizopus symbiosis.

Lackner G, Möbius N, Scherlach K, Partida-Martinez LP, Winkler R, Schmitt I, Hertweck C. Lackner G, et al. Among authors: scherlach k. Appl Environ Microbiol. 2009 May;75(9):2982-6. doi: 10.1128/AEM.01765-08. Epub 2009 Mar 13. Appl Environ Microbiol. 2009. PMID: 19286793 Free PMC article.

10

Triggering cryptic natural product biosynthesis in microorganisms.

Scherlach K, Hertweck C. Scherlach K, et al. Org Biomol Chem. 2009 May 7;7(9):1753-60. doi: 10.1039/b821578b. Epub 2009 Mar 6. Org Biomol Chem. 2009. PMID: 19590766

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