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Direct transposition of native DNA for sensitive multimodal single-molecule sequencing.
Nanda AS, Wu K, Irkliyenko I, Woo B, Ostrowski MS, Clugston AS, Sayles LC, Xu L, Satpathy AT, Nguyen HG, Alejandro Sweet-Cordero E, Goodarzi H, Kasinathan S, Ramani V. Nanda AS, et al. Among authors: goodarzi h. Nat Genet. 2024 Jun;56(6):1300-1309. doi: 10.1038/s41588-024-01748-0. Epub 2024 May 9. Nat Genet. 2024. PMID: 38724748 Free PMC article.
The DNA methylation landscape of advanced prostate cancer.
Zhao SG, Chen WS, Li H, Foye A, Zhang M, Sjöström M, Aggarwal R, Playdle D, Liao A, Alumkal JJ, Das R, Chou J, Hua JT, Barnard TJ, Bailey AM, Chow ED, Perry MD, Dang HX, Yang R, Moussavi-Baygi R, Zhang L, Alshalalfa M, Laura Chang S, Houlahan KE, Shiah YJ, Beer TM, Thomas G, Chi KN, Gleave M, Zoubeidi A, Reiter RE, Rettig MB, Witte O, Yvonne Kim M, Fong L, Spratt DE, Morgan TM, Bose R, Huang FW, Li H, Chesner L, Shenoy T, Goodarzi H, Asangani IA, Sandhu S, Lang JM, Mahajan NP, Lara PN, Evans CP, Febbo P, Batzoglou S, Knudsen KE, He HH, Huang J, Zwart W, Costello JF, Luo J, Tomlins SA, Wyatt AW, Dehm SM, Ashworth A, Gilbert LA, Boutros PC, Farh K, Chinnaiyan AM, Maher CA, Small EJ, Quigley DA, Feng FY. Zhao SG, et al. Among authors: goodarzi h. Nat Genet. 2020 Aug;52(8):778-789. doi: 10.1038/s41588-020-0648-8. Epub 2020 Jul 13. Nat Genet. 2020. PMID: 32661416 Free PMC article.
Massively multiplex single-molecule oligonucleosome footprinting.
Abdulhay NJ, McNally CP, Hsieh LJ, Kasinathan S, Keith A, Estes LS, Karimzadeh M, Underwood JG, Goodarzi H, Narlikar GJ, Ramani V. Abdulhay NJ, et al. Among authors: goodarzi h. Elife. 2020 Dec 2;9:e59404. doi: 10.7554/eLife.59404. Elife. 2020. PMID: 33263279 Free PMC article.
ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance.
Xu Y, Huangyang P, Wang Y, Xue L, Devericks E, Nguyen HG, Yu X, Oses-Prieto JA, Burlingame AL, Miglani S, Goodarzi H, Ruggero D. Xu Y, et al. Among authors: goodarzi h. Cell. 2021 Sep 30;184(20):5215-5229.e17. doi: 10.1016/j.cell.2021.08.036. Epub 2021 Sep 23. Cell. 2021. PMID: 34559986 Free PMC article.
Nucleosome density shapes kilobase-scale regulation by a mammalian chromatin remodeler.
Abdulhay NJ, Hsieh LJ, McNally CP, Ostrowski MS, Moore CM, Ketavarapu M, Kasinathan S, Nanda AS, Wu K, Chio US, Zhou Z, Goodarzi H, Narlikar GJ, Ramani V. Abdulhay NJ, et al. Among authors: goodarzi h. Nat Struct Mol Biol. 2023 Oct;30(10):1571-1581. doi: 10.1038/s41594-023-01093-6. Epub 2023 Sep 11. Nat Struct Mol Biol. 2023. PMID: 37696956 Free PMC article.
Systematic annotation of orphan RNAs reveals blood-accessible molecular barcodes of cancer identity and cancer-emergent oncogenic drivers.
Wang J, Suh JM, Woo BJ, Navickas A, Garcia K, Yin K, Fish L, Cavazos T, Hänisch B, Markett D, Yu S, Hirst G, Brown-Swigart L, Esserman LJ, van 't Veer LJ, Goodarzi H. Wang J, et al. Among authors: goodarzi h. bioRxiv [Preprint]. 2024 Mar 21:2024.03.19.585748. doi: 10.1101/2024.03.19.585748. bioRxiv. 2024. PMID: 38562907 Free PMC article. Preprint.
Systematic identification of post-transcriptional regulatory modules.
Khoroshkin M, Buyan A, Dodel M, Navickas A, Yu J, Trejo F, Doty A, Baratam R, Zhou S, Lee SB, Joshi T, Garcia K, Choi B, Miglani S, Subramanyam V, Modi H, Carpenter C, Markett D, Corces MR, Mardakheh FK, Kulakovskiy IV, Goodarzi H. Khoroshkin M, et al. Among authors: goodarzi h. Nat Commun. 2024 Sep 9;15(1):7872. doi: 10.1038/s41467-024-52215-7. Nat Commun. 2024. PMID: 39251607 Free PMC article.
Asparagine bioavailability governs metastasis in a model of breast cancer.
Knott SRV, Wagenblast E, Khan S, Kim SY, Soto M, Wagner M, Turgeon MO, Fish L, Erard N, Gable AL, Maceli AR, Dickopf S, Papachristou EK, D'Santos CS, Carey LA, Wilkinson JE, Harrell JC, Perou CM, Goodarzi H, Poulogiannis G, Hannon GJ. Knott SRV, et al. Among authors: goodarzi h. Nature. 2018 Feb 15;554(7692):378-381. doi: 10.1038/nature25465. Epub 2018 Feb 7. Nature. 2018. PMID: 29414946 Free PMC article.
Tumoural activation of TLR3-SLIT2 axis in endothelium drives metastasis.
Tavora B, Mederer T, Wessel KJ, Ruffing S, Sadjadi M, Missmahl M, Ostendorf BN, Liu X, Kim JY, Olsen O, Welm AL, Goodarzi H, Tavazoie SF. Tavora B, et al. Among authors: goodarzi h. Nature. 2020 Oct;586(7828):299-304. doi: 10.1038/s41586-020-2774-y. Epub 2020 Sep 30. Nature. 2020. PMID: 32999457 Free PMC article.
191 results