Meyer EA - Search Results

1

Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases.

Meyer EA, Croxford AL, Gnerre C, Kulig P, Murphy MJ, Jacob EM, Schäfer G, Richard-Bildstein S, Aissaoui H, Bouis P, Ertel EA, de Kanter R, Keller MP, Lüthi U, Caroff E. Meyer EA, et al. J Med Chem. 2024 May 23;67(10):8077-8098. doi: 10.1021/acs.jmedchem.4c00186. Epub 2024 May 10. J Med Chem. 2024. PMID: 38727100

2

Discovery and In Vivo Evaluation of ACT-660602: A Potent and Selective Antagonist of the Chemokine Receptor CXCR3 for Autoimmune Diseases.

Meyer EA, Äänismaa P, Froidevaux S, Keller M, Piali L, Caroff E. Meyer EA, et al. J Med Chem. 2022 Sep 8;65(17):11513-11532. doi: 10.1021/acs.jmedchem.2c00675. Epub 2022 Aug 10. J Med Chem. 2022. PMID: 35947786

3

Design, Synthesis, and Pharmacological Evaluation of Benzimidazolo-thiazoles as Potent CXCR3 Antagonists with Therapeutic Potential in Autoimmune Diseases: Discovery of ACT-672125.

Caroff E, Meyer EA, Äänismaa P, Froidevaux S, Keller M, Piali L. Caroff E, et al. Among authors: meyer ea. J Med Chem. 2022 Sep 8;65(17):11533-11549. doi: 10.1021/acs.jmedchem.2c00676. Epub 2022 Aug 15. J Med Chem. 2022. PMID: 35969159

4

Discovery of Clinical Candidate ACT-777991, a Potent CXCR3 Antagonist for Antigen-Driven and Inflammatory Pathologies.

Meyer EA, Äänismaa P, Ertel EA, Hühn E, Strasser DS, Rey M, Murphy MJ, Martinic MM, Pouzol L, Froidevaux S, Keller MP, Caroff E. Meyer EA, et al. J Med Chem. 2023 Mar 23;66(6):4179-4196. doi: 10.1021/acs.jmedchem.3c00074. Epub 2023 Mar 8. J Med Chem. 2023. PMID: 36883854

5

Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y(12) antagonists for inhibition of platelet aggregation.

Caroff E, Meyer E, Treiber A, Hilpert K, Riederer MA. Caroff E, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4323-31. doi: 10.1016/j.bmcl.2014.06.070. Epub 2014 Jul 1. Bioorg Med Chem Lett. 2014. PMID: 25113932

6

4-((R)-2-{[6-((S)-3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel.

Caroff E, Hubler F, Meyer E, Renneberg D, Gnerre C, Treiber A, Rey M, Hess P, Steiner B, Hilpert K, Riederer MA. Caroff E, et al. J Med Chem. 2015 Dec 10;58(23):9133-53. doi: 10.1021/acs.jmedchem.5b00933. Epub 2015 Nov 18. J Med Chem. 2015. PMID: 26550844

7

Assessing the mediating role of emotion regulation and experiential avoidance within a posttraumatic stress disorder and racial trauma framework.

Cole TA, Dubuclet CM, Valentine J, Meyer EA, Orcutt HK. Cole TA, et al. Among authors: meyer ea. Psychol Trauma. 2024 Feb;16(2):254-261. doi: 10.1037/tra0001487. Epub 2023 Apr 13. Psychol Trauma. 2024. PMID: 37053407

8

Current Marijuana Use and Alcohol Consumption Among Adults Following the Legalization of Nonmedical Retail Marijuana Sales - Colorado, 2015-2019.

Crawford KA, Gardner JA, Meyer EA, Hall KE, Gary DS, Esser MB. Crawford KA, et al. Among authors: meyer ea. MMWR Morb Mortal Wkly Rep. 2021 Oct 29;70(43):1505-1508. doi: 10.15585/mmwr.mm7043a3. MMWR Morb Mortal Wkly Rep. 2021. PMID: 34710079 Free PMC article.

9

Physiological and morphological correlates of extreme acid tolerance in larvae of the acidophilic amphibian Litoria cooloolensis.

Meyer EA, Franklin CE, Cramp RL. Meyer EA, et al. J Comp Physiol B. 2021 Jan;191(1):159-171. doi: 10.1007/s00360-020-01316-y. Epub 2020 Oct 1. J Comp Physiol B. 2021. PMID: 33001282

10

Aripiprazole and environmental enrichment independently improve functional outcome after cortical impact injury in adult male rats, but their combination does not yield additional benefits.

Besagar S, Radabaugh HL, Bleimeister IH, Meyer EA, Niesman PJ, Cheng JP, Bondi CO, Kline AE. Besagar S, et al. Among authors: meyer ea. Exp Neurol. 2019 Apr;314:67-73. doi: 10.1016/j.expneurol.2019.01.010. Epub 2019 Jan 17. Exp Neurol. 2019. PMID: 30659800 Free PMC article.

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