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Cross-Neutralization of Emerging SARS-CoV-2 Variants of Concern by Antibodies Targeting Distinct Epitopes on Spike.
Changrob S, Fu Y, Guthmiller JJ, Halfmann PJ, Li L, Stamper CT, Dugan HL, Accola M, Rehrauer W, Zheng NY, Huang M, Wang J, Erickson SA, Utset HA, Graves HM, Amanat F, Sather DN, Krammer F, Kawaoka Y, Wilson PC. Changrob S, et al. Among authors: guthmiller jj. mBio. 2021 Dec 21;12(6):e0297521. doi: 10.1128/mBio.02975-21. Epub 2021 Nov 16. mBio. 2021. PMID: 34781736 Free PMC article. Clinical Trial.
Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity.
Surette FA, Guthmiller JJ, Li L, Sturtz AJ, Vijay R, Pope RL, McClellan BL, Pack AD, Zander RA, Shao P, Lan LY, Fernandez-Ruiz D, Heath WR, Wilson PC, Butler NS. Surette FA, et al. Among authors: guthmiller jj. PLoS Pathog. 2021 Feb 2;17(2):e1009288. doi: 10.1371/journal.ppat.1009288. eCollection 2021 Feb. PLoS Pathog. 2021. PMID: 33529242 Free PMC article.
SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike.
Guthmiller JJ, Stovicek O, Wang J, Changrob S, Li L, Halfmann P, Zheng NY, Utset H, Stamper CT, Dugan HL, Miller WD, Huang M, Dai YN, Nelson CA, Hall PD, Jansen M, Shanmugarajah K, Donington JS, Krammer F, Fremont DH, Joachimiak A, Kawaoka Y, Tesic V, Madariaga ML, Wilson PC. Guthmiller JJ, et al. bioRxiv [Preprint]. 2020 Sep 13:2020.09.12.294066. doi: 10.1101/2020.09.12.294066. bioRxiv. 2020. Update in: mBio. 2021 Jan 19;12(1):e02940-20. doi: 10.1128/mBio.02940-20 PMID: 32935099 Free PMC article. Updated. Preprint.
Th1-like Plasmodium-Specific Memory CD4+ T Cells Support Humoral Immunity.
Zander RA, Vijay R, Pack AD, Guthmiller JJ, Graham AC, Lindner SE, Vaughan AM, Kappe SHI, Butler NS. Zander RA, et al. Among authors: guthmiller jj. Cell Rep. 2017 Nov 14;21(7):1839-1852. doi: 10.1016/j.celrep.2017.10.077. Cell Rep. 2017. PMID: 29141217 Free PMC article.
Immunogenicity of chimeric haemagglutinin-based, universal influenza virus vaccine candidates: interim results of a randomised, placebo-controlled, phase 1 clinical trial.
Bernstein DI, Guptill J, Naficy A, Nachbagauer R, Berlanda-Scorza F, Feser J, Wilson PC, Solórzano A, Van der Wielen M, Walter EB, Albrecht RA, Buschle KN, Chen YQ, Claeys C, Dickey M, Dugan HL, Ermler ME, Freeman D, Gao M, Gast C, Guthmiller JJ, Hai R, Henry C, Lan LY, McNeal M, Palm AE, Shaw DG, Stamper CT, Sun W, Sutton V, Tepora ME, Wahid R, Wenzel H, Wohlbold TJ, Innis BL, García-Sastre A, Palese P, Krammer F. Bernstein DI, et al. Among authors: guthmiller jj. Lancet Infect Dis. 2020 Jan;20(1):80-91. doi: 10.1016/S1473-3099(19)30393-7. Epub 2019 Oct 17. Lancet Infect Dis. 2020. PMID: 31630990 Free PMC article. Clinical Trial.
It's Hard to Teach an Old B Cell New Tricks.
Guthmiller JJ, Wilson PC. Guthmiller JJ, et al. Cell. 2020 Jan 9;180(1):18-20. doi: 10.1016/j.cell.2019.12.019. Cell. 2020. PMID: 31951517 Free article.
44 results