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Susceptibility of Melanoma Cells to Targeted Therapy Correlates with Protection by Blood Neutrophils.
Wendlinger S, Wohlfarth J, Siedel C, Kreft S, Kilian T, Junker S, Schmid L, Sinnberg T, Dischinger U, Heppt MV, Wistuba-Hamprecht K, Meier F, Erpenbeck L, Neubert E, Goebeler M, Gesierich A, Schrama D, Kosnopfel C, Schilling B. Wendlinger S, et al. Among authors: siedel c. Cancers (Basel). 2024 May 2;16(9):1767. doi: 10.3390/cancers16091767. Cancers (Basel). 2024. PMID: 38730718 Free PMC article.
The identification of patient-specific mutations reveals dual pathway activation in most patients with melanoma and activated receptor tyrosine kinases in BRAF/NRAS wild-type melanomas.
Appenzeller S, Gesierich A, Thiem A, Hufnagel A, Jessen C, Kneitz H, Regensburger M, Schmidt C, Zirkenbach V, Bischler T, Schilling B, Siedel C, Goebeler ME, Houben R, Schrama D, Gehrig A, Rost S, Maurus K, Bargou R, Rosenwald A, Schartl M, Goebeler M, Meierjohann S. Appenzeller S, et al. Among authors: siedel c. Cancer. 2019 Feb 15;125(4):586-600. doi: 10.1002/cncr.31843. Epub 2018 Dec 18. Cancer. 2019. PMID: 30561760 Free article.
Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion.
Kosnopfel C, Wendlinger S, Niessner H, Siewert J, Sinnberg T, Hofmann A, Wohlfarth J, Schrama D, Berthold M, Siedel C, Sauer B, Jayanthan A, Lenz G, Dunn SE, Schilling B, Schittek B. Kosnopfel C, et al. Among authors: siedel c. J Exp Clin Cancer Res. 2023 Jul 19;42(1):175. doi: 10.1186/s13046-023-02755-5. J Exp Clin Cancer Res. 2023. PMID: 37464364 Free PMC article.
Loss of p14 diminishes immunogenicity in melanoma via non-canonical Wnt signaling by reducing the peptide surface density.
Wohlfarth J, Kosnopfel C, Faber D, Berthold M, Siedel C, Bernhardt M, Schlosser A, Aprati T, Liu D, Schrama D, Houben R, Schadendorf D, Goebeler M, Meierjohann S, Schilling B. Wohlfarth J, et al. Among authors: siedel c. Mol Oncol. 2024 Oct;18(10):2449-2470. doi: 10.1002/1878-0261.13660. Epub 2024 May 28. Mol Oncol. 2024. PMID: 38807304 Free PMC article.
In situ cytokine therapy: redistribution of clonally expanded T cells.
thor Straten P, Guldberg P, Schrama D, Andersen MH, Moerch U, Seremet T, Siedel C, Reisfeld RA, Becker JC. thor Straten P, et al. Among authors: siedel c. Eur J Immunol. 2001 Jan;31(1):250-8. doi: 10.1002/1521-4141(200101)31:1<250::AID-IMMU250>3.0.CO;2-8. Eur J Immunol. 2001. PMID: 11265641 Free article.