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Genome-wide detection of DNA double-strand breaks by in-suspension BLISS.
Bouwman BAM, Agostini F, Garnerone S, Petrosino G, Gothe HJ, Sayols S, Moor AE, Itzkovitz S, Bienko M, Roukos V, Crosetto N. Bouwman BAM, et al. Among authors: roukos v. Nat Protoc. 2020 Dec;15(12):3894-3941. doi: 10.1038/s41596-020-0397-2. Epub 2020 Nov 2. Nat Protoc. 2020. PMID: 33139954
Territories or spaghetti? Chromosome organization exposed.
Longo GMC, Roukos V. Longo GMC, et al. Among authors: roukos v. Nat Rev Mol Cell Biol. 2021 Aug;22(8):508. doi: 10.1038/s41580-021-00372-8. Nat Rev Mol Cell Biol. 2021. PMID: 33854243 No abstract available.
High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue.
Zhang N, Harbers L, Simonetti M, Diekmann C, Verron Q, Berrino E, Bellomo SE, Longo GMC, Ratz M, Schultz N, Tarish F, Su P, Han B, Wang W, Onorato S, Grassini D, Ballarino R, Giordano S, Yang Q, Sapino A, Frisén J, Alkass K, Druid H, Roukos V, Helleday T, Marchiò C, Bienko M, Crosetto N. Zhang N, et al. Among authors: roukos v. Nat Commun. 2024 Apr 24;15(1):3475. doi: 10.1038/s41467-024-47664-z. Nat Commun. 2024. PMID: 38658552 Free PMC article.
Spatial Chromosome Folding and Active Transcription Drive DNA Fragility and Formation of Oncogenic MLL Translocations.
Gothe HJ, Bouwman BAM, Gusmao EG, Piccinno R, Petrosino G, Sayols S, Drechsel O, Minneker V, Josipovic N, Mizi A, Nielsen CF, Wagner EM, Takeda S, Sasanuma H, Hudson DF, Kindler T, Baranello L, Papantonis A, Crosetto N, Roukos V. Gothe HJ, et al. Among authors: roukos v. Mol Cell. 2019 Jul 25;75(2):267-283.e12. doi: 10.1016/j.molcel.2019.05.015. Epub 2019 Jun 12. Mol Cell. 2019. PMID: 31202576 Free article.
RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1.
Abu-Libdeh B, Jhujh SS, Dhar S, Sommers JA, Datta A, Longo GM, Grange LJ, Reynolds JJ, Cooke SL, McNee GS, Hollingworth R, Woodward BL, Ganesh AN, Smerdon SJ, Nicolae CM, Durlacher-Betzer K, Molho-Pessach V, Abu-Libdeh A, Meiner V, Moldovan GL, Roukos V, Harel T, Brosh RM Jr, Stewart GS. Abu-Libdeh B, et al. Among authors: roukos v. J Clin Invest. 2022 Mar 1;132(5):e147301. doi: 10.1172/JCI147301. J Clin Invest. 2022. PMID: 35025765 Free PMC article.
Cohesin puts a break on distal homology hunt.
Papantonis A, Roukos V. Papantonis A, et al. Among authors: roukos v. Nat Cell Biol. 2021 Nov;23(11):1112-1114. doi: 10.1038/s41556-021-00791-x. Nat Cell Biol. 2021. PMID: 34750579 No abstract available.
38 results