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Antibodies expand the scope of angiotensin receptor pharmacology.
Skiba MA, Sterling SM, Rawson S, Zhang S, Xu H, Jiang H, Nemeth GR, Gilman MSA, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Rockman HA, Barth P, Wingler LM, Kruse AC. Skiba MA, et al. Nat Chem Biol. 2024 Dec;20(12):1577-1585. doi: 10.1038/s41589-024-01620-6. Epub 2024 May 14. Nat Chem Biol. 2024. PMID: 38744986
Antibodies Expand the Scope of Angiotensin Receptor Pharmacology.
Skiba MA, Sterling SM, Rawson S, Gilman MSA, Xu H, Nemeth GR, Hurley JD, Shen P, Staus DP, Kim J, McMahon C, Lehtinen MK, Wingler LM, Kruse AC. Skiba MA, et al. bioRxiv [Preprint]. 2023 Aug 24:2023.08.23.554128. doi: 10.1101/2023.08.23.554128. bioRxiv. 2023. Update in: Nat Chem Biol. 2024 Dec;20(12):1577-1585. doi: 10.1038/s41589-024-01620-6 PMID: 37662341 Free PMC article. Updated. Preprint.
Synthetic nanobodies as angiotensin receptor blockers.
McMahon C, Staus DP, Wingler LM, Wang J, Skiba MA, Elgeti M, Hubbell WL, Rockman HA, Kruse AC, Lefkowitz RJ. McMahon C, et al. Among authors: skiba ma. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20284-20291. doi: 10.1073/pnas.2009029117. Epub 2020 Aug 4. Proc Natl Acad Sci U S A. 2020. PMID: 32753386 Free PMC article.
Autoantibodies as Endogenous Modulators of GPCR Signaling.
Skiba MA, Kruse AC. Skiba MA, et al. Trends Pharmacol Sci. 2021 Mar;42(3):135-150. doi: 10.1016/j.tips.2020.11.013. Epub 2020 Dec 24. Trends Pharmacol Sci. 2021. PMID: 33358695 Free PMC article. Review.
An in silico method to assess antibody fragment polyreactivity.
Harvey EP, Shin JE, Skiba MA, Nemeth GR, Hurley JD, Wellner A, Shaw AY, Miranda VG, Min JK, Liu CC, Marks DS, Kruse AC. Harvey EP, et al. Among authors: skiba ma. Nat Commun. 2022 Dec 7;13(1):7554. doi: 10.1038/s41467-022-35276-4. Nat Commun. 2022. PMID: 36477674 Free PMC article.
Virtual Screening for Ligand Discovery at the σ1 Receptor.
Greenfield DA, Schmidt HR, Skiba MA, Mandler MD, Anderson JR, Sliz P, Kruse AC. Greenfield DA, et al. Among authors: skiba ma. ACS Med Chem Lett. 2020 Jul 27;11(8):1555-1561. doi: 10.1021/acsmedchemlett.9b00314. eCollection 2020 Aug 13. ACS Med Chem Lett. 2020. PMID: 32832023 Free PMC article.
46 results