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Gelling hypotonic polymer solution for extended topical drug delivery to the eye.
Kim YC, Shin MD, Hackett SF, Hsueh HT, Lima E Silva R, Date A, Han H, Kim BJ, Xiao A, Kim Y, Ogunnaike L, Anders NM, Hemingway A, He P, Jun AS, McDonnell PJ, Eberhart C, Pitha I, Zack DJ, Campochiaro PA, Hanes J, Ensign LM. Kim YC, et al. Nat Biomed Eng. 2020 Nov;4(11):1053-1062. doi: 10.1038/s41551-020-00606-8. Epub 2020 Sep 7. Nat Biomed Eng. 2020. PMID: 32895514 Free PMC article.
Preclinical evaluation of a hypotonic docetaxel nanosuspension formulation for intravesical treatment of non-muscle-invasive bladder cancer.
Date AA, Kates M, Yoshida T, Babu T, Afzal U, Kanvinde P, Baras A, Anders N, He P, Rudek M, Hanes J, Bivalacqua TJ, Ensign LM. Date AA, et al. Among authors: anders n. Drug Deliv Transl Res. 2021 Oct;11(5):2085-2095. doi: 10.1007/s13346-020-00870-w. Epub 2020 Nov 8. Drug Deliv Transl Res. 2021. PMID: 33164163 Free PMC article.
A hypotonic gel-forming eye drop provides enhanced intraocular delivery of a kinase inhibitor with melanin-binding properties for sustained protection of retinal ganglion cells.
Kim YC, Hsueh HT, Shin MD, Berlinicke CA, Han H, Anders NM, Hemingway A, Leo KT, Chou RT, Kwon H, Appell MB, Rai U, Kolodziejski P, Eberhart C, Pitha I, Zack DJ, Hanes J, Ensign LM. Kim YC, et al. Drug Deliv Transl Res. 2022 Apr;12(4):826-837. doi: 10.1007/s13346-021-00987-6. Epub 2021 Apr 26. Drug Deliv Transl Res. 2022. PMID: 33900546 Free PMC article.
Ion-Complex Microcrystal Formulation Provides Sustained Delivery of a Multimodal Kinase Inhibitor from the Subconjunctival Space for Protection of Retinal Ganglion Cells.
Hsueh HT, Kim YC, Pitha I, Shin MD, Berlinicke CA, Chou RT, Kimball E, Schaub J, Quillen S, Leo KT, Han H, Xiao A, Kim Y, Appell M, Rai U, Kwon H, Kolodziejski P, Ogunnaike L, Anders NM, Hemingway A, Jefferys JL, Date AA, Eberhart C, Johnson TV, Quigley HA, Zack DJ, Hanes J, Ensign LM. Hsueh HT, et al. Pharmaceutics. 2021 May 1;13(5):647. doi: 10.3390/pharmaceutics13050647. Pharmaceutics. 2021. PMID: 34062883 Free PMC article.
173 results