Li D - Search Results

1

A potent new-scaffold androgen receptor antagonist discovered on the basis of a MIEC-SVM model.

Wang XY, Chai X, Shan LH, Xu XH, Xu L, Hou TJ, Sun HY, Li D. Wang XY, et al. Among authors: li d. Acta Pharmacol Sin. 2024 Sep;45(9):1978-1991. doi: 10.1038/s41401-024-01284-x. Epub 2024 May 15. Acta Pharmacol Sin. 2024. PMID: 38750073

2

ReMODE: a deep learning-based web server for target-specific drug design.

Wang M, Wang J, Weng G, Kang Y, Pan P, Li D, Deng Y, Li H, Hsieh CY, Hou T. Wang M, et al. Among authors: li d, li h. J Cheminform. 2022 Dec 12;14(1):84. doi: 10.1186/s13321-022-00665-w. J Cheminform. 2022. PMID: 36510307 Free PMC article.

3

Computationally guided discovery of novel non-steroidal AR-GR dual antagonists demonstrating potency against antiandrogen resistance.

Chai X, Hu XP, Wang XY, Wang HT, Pang JP, Zhou WF, Liao JN, Shan LH, Xu XH, Xu L, Xia HG, Hou TJ, Li D. Chai X, et al. Among authors: li d. Acta Pharmacol Sin. 2023 Jul;44(7):1500-1518. doi: 10.1038/s41401-022-01038-7. Epub 2023 Jan 13. Acta Pharmacol Sin. 2023. PMID: 36639570 Free PMC article.

4

Recent advances in the development of DprE1 inhibitors using AI/CADD approaches.

Chen K, Xu R, Hu X, Li D, Hou T, Kang Y. Chen K, et al. Among authors: li d. Drug Discov Today. 2024 Jun;29(6):103987. doi: 10.1016/j.drudis.2024.103987. Epub 2024 Apr 25. Drug Discov Today. 2024. PMID: 38670256 Review.

5

ClickGen: Directed exploration of synthesizable chemical space via modular reactions and reinforcement learning.

Wang M, Li S, Wang J, Zhang O, Du H, Jiang D, Wu Z, Deng Y, Kang Y, Pan P, Li D, Wang X, Yao X, Hou T, Hsieh CY. Wang M, et al. Among authors: li s, li d. Nat Commun. 2024 Nov 22;15(1):10127. doi: 10.1038/s41467-024-54456-y. Nat Commun. 2024. PMID: 39578485 Free PMC article.

6

The design, synthesis and bioactivity evaluation of novel androgen receptor degraders based on hydrophobic tagging.

Sun Y, Wang H, Li Y, Li Z, Mao Z, Zhang M, Shao Y, Ye J, Li D, Shan L. Sun Y, et al. Among authors: li d, li y, li z. Bioorg Chem. 2024 May;146:107309. doi: 10.1016/j.bioorg.2024.107309. Epub 2024 Mar 24. Bioorg Chem. 2024. PMID: 38537338

7

How to promote the healthy development of continuous participation in smart medical and elderly care systems: The dual perspective of perceived value and risk.

Cao C, Dai H, Li D. Cao C, et al. Among authors: li d. Digit Health. 2023 Aug 28;9:20552076231197425. doi: 10.1177/20552076231197425. eCollection 2023 Jan-Dec. Digit Health. 2023. PMID: 37654713 Free PMC article.

8

A clinical prediction model for the presence of brain metastases from colorectal cancer.

Ge X, Li D, Ye X, Ma R, Yuan Y. Ge X, et al. Among authors: li d. Int J Colorectal Dis. 2022 Dec;37(12):2469-2480. doi: 10.1007/s00384-022-04289-2. Epub 2022 Dec 2. Int J Colorectal Dis. 2022. PMID: 36459181

9

Aldo-keto reductase-7A2 protects against atorvastatin-induced hepatotoxicity via Nrf2 activation.

Li D, Chen J, Zhou F, Zhang W, Chen H. Li D, et al. Chem Biol Interact. 2024 Apr 25;393:110956. doi: 10.1016/j.cbi.2024.110956. Epub 2024 Mar 12. Chem Biol Interact. 2024. PMID: 38484826

10

Forced degradation studies of elagolix sodium with the implementation of high resolution LC-UV-PDA-MSⁿ (n = 1,2,3…) and NMR structural elucidation.

Zhong X, Lv Q, Yong Q, Hu W, Li D, Ji S, Zhan L, Chen W, Li M, Lin J, Sun C. Zhong X, et al. Among authors: li d, li m. J Pharm Biomed Anal. 2023 Feb 5;224:115198. doi: 10.1016/j.jpba.2022.115198. Epub 2022 Dec 5. J Pharm Biomed Anal. 2023. PMID: 36495708

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