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226 results

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Page 1
A Bispecific Monoclonal Antibody Targeting Psl and PcrV Enhances Neutrophil-Mediated Killing of Pseudomonas aeruginosa in Patients with Bronchiectasis.
Long MB, Gilmour A, Kehl M, Tabor DE, Keller AE, Warrener P, Gopalakrishnan V, Rosengren S, Crichton ML, McIntosh E, Giam YH, Keir HR, Brailsford W, Hughes R, Belvisi MG, Sellman BR, DiGiandomenico A, Chalmers JD. Long MB, et al. Among authors: belvisi mg. Am J Respir Crit Care Med. 2024 Jul 1;210(1):35-46. doi: 10.1164/rccm.202308-1403OC. Am J Respir Crit Care Med. 2024. PMID: 38754132
Deep Learning-based Segmentation of Computed Tomography Scans Predicts Disease Progression and Mortality in Idiopathic Pulmonary Fibrosis.
Thillai M, Oldham JM, Ruggiero A, Kanavati F, McLellan T, Saini G, Johnson SR, Ble FX, Azim A, Ostridge K, Platt A, Belvisi M, Maher TM, Molyneaux PL. Thillai M, et al. Am J Respir Crit Care Med. 2024 Aug 15;210(4):465-472. doi: 10.1164/rccm.202311-2185OC. Am J Respir Crit Care Med. 2024. PMID: 38452227 Free PMC article.
Genetic architecture of telomere length in 462,666 UK Biobank whole-genome sequences.
Burren OS, Dhindsa RS, Deevi SVV, Wen S, Nag A, Mitchell J, Hu F, Loesch DP, Smith KR, Razdan N, Olsson H, Platt A, Vitsios D, Wu Q; AstraZeneca Genomics Initiative; Codd V, Nelson CP, Samani NJ, March RE, Wasilewski S, Carss K, Fabre M, Wang Q, Pangalos MN, Petrovski S. Burren OS, et al. Nat Genet. 2024 Sep;56(9):1832-1840. doi: 10.1038/s41588-024-01884-7. Epub 2024 Aug 27. Nat Genet. 2024. PMID: 39192095 Free PMC article.
Efficacy and safety of tozorakimab in moderate-to-severe atopic dermatitis: A Phase 2a randomized controlled trial (FRONTIER-2).
Silverberg JI, Mustapa MN, Reid F, Lei A, Smith R, Moate R, Kelly A, Chen R, Gavala M, Jimenez E, Belvisi MG, Sadiq MW, Kell C, Pandya HC. Silverberg JI, et al. Among authors: belvisi mg. J Eur Acad Dermatol Venereol. 2024 Nov 13. doi: 10.1111/jdv.20388. Online ahead of print. J Eur Acad Dermatol Venereol. 2024. PMID: 39535462
AZD9567 versus prednisolone in patients with active rheumatoid arthritis: A phase IIa, randomized, double-blind, efficacy, and safety study.
van Laar JM, Lei A, Safy-Khan M, Almquist J, Belfield G, Edman K, Öberg L, Angermann BR, Dillmann I, Berntsson P, Etal D, Dainty I, Astbury C, Belvisi MG, Nemes S, Platt A, Prothon S, Samuelsson S, Svanberg P, Keen C; SEMRA study group. van Laar JM, et al. Among authors: belvisi mg. Clin Transl Sci. 2023 Dec;16(12):2494-2506. doi: 10.1111/cts.13624. Epub 2023 Oct 23. Clin Transl Sci. 2023. PMID: 37873558 Free PMC article. Clinical Trial.
Rare variant associations with plasma protein levels in the UK Biobank.
Dhindsa RS, Burren OS, Sun BB, Prins BP, Matelska D, Wheeler E, Mitchell J, Oerton E, Hristova VA, Smith KR, Carss K, Wasilewski S, Harper AR, Paul DS, Fabre MA, Runz H, Viollet C, Challis B, Platt A; AstraZeneca Genomics Initiative; Vitsios D, Ashley EA, Whelan CD, Pangalos MN, Wang Q, Petrovski S. Dhindsa RS, et al. Nature. 2023 Oct;622(7982):339-347. doi: 10.1038/s41586-023-06547-x. Epub 2023 Oct 4. Nature. 2023. PMID: 37794183 Free PMC article.
PI3Kγδ inhibition suppresses key disease features in a rat model of asthma.
Pinkerton JW, Preite S, Piras A, Zervas D, Markou T, Freeman MS, Hofving T, Ivarsson E, Bonvini SJ, Brailsford W, Yrlid L, Belvisi MG, Birrell MA. Pinkerton JW, et al. Among authors: belvisi mg. Respir Res. 2024 Apr 23;25(1):175. doi: 10.1186/s12931-024-02814-1. Respir Res. 2024. PMID: 38654248 Free PMC article.
Multiomics links global surfactant dysregulation with airflow obstruction and emphysema in COPD.
Hristova VA, Watson A, Chaerkady R, Glover MS, Ackland J, Angerman B, Belfield G, Belvisi MG, Burke H, Cellura D, Clark HW, Etal D, Freeman A, Heinson AI, Hess S, Hühn M, Hall E, Mackay A, Madsen J, McCrae C, Muthas D, Novick S, Ostridge K, Öberg L, Platt A, Postle AD, Spalluto CM, Vaarala O, Wang J, Staples KJ, Wilkinson TMA; MICA II Study group. Hristova VA, et al. Among authors: belvisi mg. ERJ Open Res. 2022 May 15;9(3):00378-2022. doi: 10.1183/23120541.00378-2022. eCollection 2023 May. ERJ Open Res. 2022. PMID: 37228288 Free PMC article.
The Burden and Impact of Cough in Patients with Idiopathic Pulmonary Fibrosis: An Analysis of the Prospective Observational PROFILE Study.
Saunders P, Wu Z, Fahy WA, Stewart ID, Saini G, Smith DJF, Braybrooke R, Stock C, Renzoni EA, Johnson SR, Jenkins RG, Belvisi MG, Smith JA, Maher TM, Molyneaux PL. Saunders P, et al. Among authors: belvisi mg. Ann Am Thorac Soc. 2023 Sep;20(9):1267-1273. doi: 10.1513/AnnalsATS.202302-174OC. Ann Am Thorac Soc. 2023. PMID: 37159951 Free PMC article.
Characterization of Selective and Potent JAK1 Inhibitors Intended for the Inhaled Treatment of Asthma.
Nilsson M, Rhedin M, Hendrickx R, Berglund S, Piras A, Blomgran P, Cavallin A, Collins M, Dahl G, Dekkak B, Ericsson T, Hagberg N, Holmberg AA, Leffler A, Lundqvist AJ, Markou T, Pinkerton J, Rönnblom L, Siu S, Taylor V, Wennberg T, Zervas D, Laurence ADJ, Mitra S, Belvisi MG, Birrell M, Borde A. Nilsson M, et al. Among authors: belvisi mg. Drug Des Devel Ther. 2022 Aug 31;16:2901-2917. doi: 10.2147/DDDT.S354291. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36068788 Free PMC article.
226 results