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Vaccination with the Crimean-Congo hemorrhagic fever virus viral replicon vaccine induces NP-based T-cell activation and antibodies possessing Fc-mediated effector functions.
Scholte FEM, Karaaslan E, O'Neal TJ, Sorvillo TE, Genzer SC, Welch SR, Coleman-McCray JD, Spengler JR, Kainulainen MH, Montgomery JM, Pegan SD, Bergeron E, Spiropoulou CF. Scholte FEM, et al. Among authors: pegan sd. Front Cell Infect Microbiol. 2023 Aug 21;13:1233148. doi: 10.3389/fcimb.2023.1233148. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37671145 Free PMC article.
Inflammation associated with monocyte/macrophage activation and recruitment corresponds with lethal outcome in a mouse model of Crimean-Congo haemorrhagic fever1.
Sorvillo TE, Ritter JM, Welch SR, Coleman-McCray JD, Davies KA, Hayes HM, Pegan SD, Montgomery JM, Bergeron É, Spiropoulou CF, Spengler JR. Sorvillo TE, et al. Among authors: pegan sd. Emerg Microbes Infect. 2024 Dec;13(1):2427782. doi: 10.1080/22221751.2024.2427782. Epub 2024 Nov 19. Emerg Microbes Infect. 2024. PMID: 39513496 Free PMC article.
Crimean Congo hemorrhagic fever virus nucleoprotein and GP38 subunit vaccine combination prevents morbidity in mice.
Karaaslan E, Sorvillo TE, Scholte FEM, O'Neal TJ, Welch SR, Davies KA, Coleman-McCray JD, Harmon JR, Ritter JM, Pegan SD, Montgomery JM, Spengler JR, Spiropoulou CF, Bergeron É. Karaaslan E, et al. Among authors: pegan sd. NPJ Vaccines. 2024 Aug 14;9(1):148. doi: 10.1038/s41541-024-00931-y. NPJ Vaccines. 2024. PMID: 39143104 Free PMC article.
Replicon particle vaccination induces non-neutralizing anti-nucleoprotein antibody-mediated control of Crimean-Congo hemorrhagic fever virus.
Sorvillo TE, Karaaslan E, Scholte FEM, Welch SR, Coleman-McCray JD, Genzer SC, Ritter JM, Hayes HM, Jain S, Pegan SD, Bergeron É, Montgomery JM, Spiropoulou CF, Spengler JR. Sorvillo TE, et al. Among authors: pegan sd. NPJ Vaccines. 2024 May 23;9(1):88. doi: 10.1038/s41541-024-00877-1. NPJ Vaccines. 2024. PMID: 38782933 Free PMC article.
Structural characterization of protective non-neutralizing antibodies targeting Crimean-Congo hemorrhagic fever virus.
Durie IA, Tehrani ZR, Karaaslan E, Sorvillo TE, McGuire J, Golden JW, Welch SR, Kainulainen MH, Harmon JR, Mousa JJ, Gonzalez D, Enos S, Koksal I, Yilmaz G, Karakoc HN, Hamidi S, Albay C, Spengler JR, Spiropoulou CF, Garrison AR, Sajadi MM, Bergeron É, Pegan SD. Durie IA, et al. Among authors: pegan sd. Nat Commun. 2022 Nov 26;13(1):7298. doi: 10.1038/s41467-022-34923-0. Nat Commun. 2022. PMID: 36435827 Free PMC article.
Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses.
Freitas BT, Ahiadorme DA, Bagul RS, Durie IA, Ghosh S, Hill J, Kramer NE, Murray J, O'Boyle BM, Onobun E, Pirrone MG, Shepard JD, Enos S, Subedi YP, Upadhyaya K, Tripp RA, Cummings BS, Crich D, Pegan SD. Freitas BT, et al. Among authors: pegan sd. ACS Infect Dis. 2022 Mar 11;8(3):596-611. doi: 10.1021/acsinfecdis.1c00631. Epub 2022 Feb 24. ACS Infect Dis. 2022. PMID: 35199517 Free PMC article.
58 results