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Mechanistic safety assessment via multi-omic characterisation of systemic pathway perturbations following in vivo MAT2A inhibition.
Fogal V, Michopoulos F, Jarnuczak AF, Hamza GM, Harlfinger S, Davey P, Hulme H, Atkinson SJ, Gabrowski P, Cheung T, Grondine M, Hoover C, Rose J, Bray C, Foster AJ, Askin S, Majumder MM, Fitzpatrick P, Miele E, Macdonald R, Keun HC, Coen M. Fogal V, et al. Among authors: keun hc. Arch Toxicol. 2024 Aug;98(8):2589-2603. doi: 10.1007/s00204-024-03771-w. Epub 2024 May 17. Arch Toxicol. 2024. PMID: 38755480 Free PMC article.
Editorial overview: Recent advances in metabolomics.
McCullagh JSO, Keun HC. McCullagh JSO, et al. Among authors: keun hc. Curr Opin Chem Biol. 2024 Aug;81:102498. doi: 10.1016/j.cbpa.2024.102498. Epub 2024 Jul 8. Curr Opin Chem Biol. 2024. PMID: 38981158 No abstract available.
PTEN Loss Shapes Macrophage Dynamics in High-Grade Serous Ovarian Carcinoma.
Spear S, Le Saux O, Mirza HB, Iyer N, Tyson K, Grundland Freile F, Walton JB, Woodman C, Jarvis S, Ennis DP, Aguirre Hernandez C, Xu Y, Spiliopoulou P, Brenton JD, Costa-Pereira AP, Cook DP, Vanderhyden BC, Keun HC, Triantafyllou E, Arnold JN, McNeish IA. Spear S, et al. Among authors: keun hc. Cancer Res. 2024 Nov 15;84(22):3772-3787. doi: 10.1158/0008-5472.CAN-23-3890. Cancer Res. 2024. PMID: 39186679 Free PMC article.
Chemical tools for profiling the intracellular ADP-ribosylated proteome.
Draganov SD, Gruet MJ, Conole D, Balcells C, Siskos AP, Keun HC, Haskard DO, Tate EW. Draganov SD, et al. Among authors: keun hc. RSC Chem Biol. 2024 May 22;5(7):640-651. doi: 10.1039/d4cb00043a. eCollection 2024 Jul 3. RSC Chem Biol. 2024. PMID: 38966672 Free PMC article.
Prenatal Exposure to Chemical Mixtures and Metabolic Syndrome Risk in Children.
Güil-Oumrait N, Stratakis N, Maitre L, Anguita-Ruiz A, Urquiza J, Fabbri L, Basagaña X, Heude B, Haug LS, Sakhi AK, Iszatt N, Keun HC, Wright J, Chatzi L, Vafeiadi M, Bustamante M, Grazuleviciene R, Andrušaityte S, Slama R, McEachan R, Casas M, Vrijheid M. Güil-Oumrait N, et al. Among authors: keun hc. JAMA Netw Open. 2024 May 1;7(5):e2412040. doi: 10.1001/jamanetworkopen.2024.12040. JAMA Netw Open. 2024. PMID: 38780942 Free PMC article.
149 results