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Engineered CRISPR-Cas12a for higher-order combinatorial chromatin perturbations.
Nat Biotechnol. 2024 May 17. doi: 10.1038/s41587-024-02224-0. Online ahead of print.
Nat Biotechnol. 2024.
PMID: 38760567
Higher-order combinatorial chromatin perturbations by engineered CRISPR-Cas12a for functional genomics.
Hsiung CC, Wilson CM, Sambold NA, Dai R, Chen Q, Misiukiewicz S, Arab A, Teyssier N, O'Loughlin T, Cofsky JC, Shi J, Gilbert LA.
Hsiung CC, et al. Among authors: sambold na.
bioRxiv [Preprint]. 2024 Feb 9:2023.09.18.558350. doi: 10.1101/2023.09.18.558350.
bioRxiv. 2024.
Update in:
Nat Biotechnol. 2024 May 17. doi: 10.1038/s41587-024-02224-0
PMID: 37781594
Free PMC article.
Updated.
Preprint.
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Biocatalytic control of site-selectivity and chain length-selectivity in radical amino acid halogenases.
Kissman EN, Neugebauer ME, Sumida KH, Swenson CV, Sambold NA, Marchand JA, Millar DC, Chang MCY.
Kissman EN, et al. Among authors: sambold na.
Proc Natl Acad Sci U S A. 2023 Mar 21;120(12):e2214512120. doi: 10.1073/pnas.2214512120. Epub 2023 Mar 13.
Proc Natl Acad Sci U S A. 2023.
PMID: 36913566
Free PMC article.
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Reaction pathway engineering converts a radical hydroxylase into a halogenase.
Neugebauer ME, Kissman EN, Marchand JA, Pelton JG, Sambold NA, Millar DC, Chang MCY.
Neugebauer ME, et al. Among authors: sambold na.
Nat Chem Biol. 2022 Feb;18(2):171-179. doi: 10.1038/s41589-021-00944-x. Epub 2021 Dec 22.
Nat Chem Biol. 2022.
PMID: 34937913
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