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COVID-19 Diarrhea Is Inflammatory, Caused by Direct Viral Effects Plus Major Role of Virus-induced Cytokines.
Donowitz M, Tse CM, Sarker R, Lin R, Dokladny K, Rawat M, Horwitz I, Ye C, McNamara G, In J, Kell A, Guo C, JuiTsai S, Vong T, Karaba A, Singh V, Sachithanandham J, Pekosz A, Cox A, Bradfute S, Zachos NC, Gould S, Kovbasnjuk O. Donowitz M, et al. Among authors: kovbasnjuk o. Cell Mol Gastroenterol Hepatol. 2024;18(5):101383. doi: 10.1016/j.jcmgh.2024.101383. Epub 2024 Jul 31. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39089626 Free PMC article.
Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.
Kim H, Villareal LB, Liu Z, Haneef M, Falcon DM, Martin DR, Lee HJ, Dame MK, Attili D, Chen Y, Varani J, Spence JR, Kovbasnjuk O, Colacino JA, Lyssiotis CA, Lin HC, Shah YM, Xue X. Kim H, et al. Among authors: kovbasnjuk o. Adv Sci (Weinh). 2023 Apr;10(10):e2207693. doi: 10.1002/advs.202207693. Epub 2023 Jan 26. Adv Sci (Weinh). 2023. PMID: 36703617 Free PMC article.
SARS-COV-2 induced Diarrhea is inflammatory, Ca 2+ Dependent and involves activation of calcium activated Cl channels.
Donowitz M, Tse CM, Dokladny K, Rawat M, Horwitz I, Ye C, Kell A, Lin R, Lee S, Guo C, Tsai SJ, Cox A, Gould S, In J, Bradfute S, Zachos NC, Kovbasnjuk O. Donowitz M, et al. Among authors: kovbasnjuk o. bioRxiv [Preprint]. 2021 Apr 28:2021.04.27.441695. doi: 10.1101/2021.04.27.441695. bioRxiv. 2021. PMID: 33948596 Free PMC article. Preprint.
Novel variants in the stem cell niche factor WNT2B define the disease phenotype as a congenital enteropathy with ocular dysgenesis.
Zhang YJ, Jimenez L, Azova S, Kremen J, Chan YM, Elhusseiny AM, Saeed H, Goldsmith J, Al-Ibraheemi A, O'Connell AE, Kovbasnjuk O, Rodan L, Agrawal PB, Thiagarajah JR. Zhang YJ, et al. Among authors: kovbasnjuk o. Eur J Hum Genet. 2021 Jun;29(6):998-1007. doi: 10.1038/s41431-021-00812-1. Epub 2021 Feb 1. Eur J Hum Genet. 2021. PMID: 33526876 Free PMC article.
78 results