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Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.
Alves M, Gil B, Villegas-Salmerón J, Salari V, Martins-Ferreira R, Arribas Blázquez M, Menéndez Méndez A, Da Rosa Gerbatin R, Smith J, de Diego-Garcia L, Conte G, Sierra-Marquez J, Merino Serrais P, Mitra M, Fernandez Martin A, Wang Y, Kesavan J, Melia C, Parras A, Beamer E, Zimmer B, Heiland M, Cavanagh B, Parcianello Cipolat R, Morgan J, Teng X, Prehn JHM, Fabene PF, Bertini G, Artalejo AR, Ballestar E, Nicke A, Olivos-Oré LA, Connolly NMC, Henshall DC, Engel T. Alves M, et al. Among authors: engel t. Brain Behav Immun. 2024 Aug;120:121-140. doi: 10.1016/j.bbi.2024.05.023. Epub 2024 May 20. Brain Behav Immun. 2024. PMID: 38777288 Free article.
Effects of transient focal cerebral ischemia in mice deficient in puma.
Kuroki K, Virard I, Concannon CG, Engel T, Woods I, Taki W, Plesnila N, Henshall DC, Prehn JH. Kuroki K, et al. Among authors: engel t. Neurosci Lett. 2009 Feb 27;451(3):237-40. doi: 10.1016/j.neulet.2009.01.019. Epub 2009 Jan 13. Neurosci Lett. 2009. PMID: 19159665
Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus.
Murphy BM, Engel T, Paucard A, Hatazaki S, Mouri G, Tanaka K, Tuffy LP, Jimenez-Mateos EM, Woods I, Dunleavy M, Bonner HP, Meller R, Simon RP, Strasser A, Prehn JH, Henshall DC. Murphy BM, et al. Among authors: engel t. Cell Death Differ. 2010 Mar;17(3):459-68. doi: 10.1038/cdd.2009.134. Epub 2009 Sep 25. Cell Death Differ. 2010. PMID: 19779495 Free PMC article.
Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma.
Engel T, Murphy BM, Hatazaki S, Jimenez-Mateos EM, Concannon CG, Woods I, Prehn JH, Henshall DC. Engel T, et al. FASEB J. 2010 Mar;24(3):853-61. doi: 10.1096/fj.09-145870. Epub 2009 Nov 4. FASEB J. 2010. PMID: 19890018 Free PMC article.
These are the first data showing genetic deletion of a proapoptotic protein acting acutely to influence neuronal death subsequently alters the phenotype of epilepsy in the long-term, supporting the concept that apoptotic pathway activation is a trigger of epileptogenesis.-Enge …
These are the first data showing genetic deletion of a proapoptotic protein acting acutely to influence neuronal death subsequently alters t …
470 results