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Page 1
Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice.
Alves M, Gil B, Villegas-Salmerón J, Salari V, Martins-Ferreira R, Arribas Blázquez M, Menéndez Méndez A, Da Rosa Gerbatin R, Smith J, de Diego-Garcia L, Conte G, Sierra-Marquez J, Merino Serrais P, Mitra M, Fernandez Martin A, Wang Y, Kesavan J, Melia C, Parras A, Beamer E, Zimmer B, Heiland M, Cavanagh B, Parcianello Cipolat R, Morgan J, Teng X, Prehn JHM, Fabene PF, Bertini G, Artalejo AR, Ballestar E, Nicke A, Olivos-Oré LA, Connolly NMC, Henshall DC, Engel T. Alves M, et al. Among authors: nicke a. Brain Behav Immun. 2024 Aug;120:121-140. doi: 10.1016/j.bbi.2024.05.023. Epub 2024 May 20. Brain Behav Immun. 2024. PMID: 38777288 Free article.
Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
Morgan J, Moreno O, Alves M, Baz Z, Menéndez Méndez A, Leister H, Melia C, Smith J, Visekruna A, Nicke A, Bhattacharya A, Ceusters M, Henshall DC, Gómez-Vallejo V, Llop J, Engel T. Morgan J, et al. Among authors: nicke a. Epilepsia. 2023 Feb;64(2):511-523. doi: 10.1111/epi.17484. Epub 2022 Dec 27. Epilepsia. 2023. PMID: 36507708 Free PMC article.
Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system-No evidence for the role of neuronal P2X7 receptors in colitis.
Jooss T, Zhang J, Zimmer B, Rezzonico-Jost T, Rissiek B, Felipe Pelczar P, Seehusen F, Koch-Nolte F, Magnus T, Zierler S, Huber S, Schemann M, Grassi F, Nicke A. Jooss T, et al. Among authors: nicke a. Mucosal Immunol. 2023 Apr;16(2):180-193. doi: 10.1016/j.mucimm.2022.11.003. Epub 2023 Jan 10. Mucosal Immunol. 2023. PMID: 36634819 Free article.
Different localization of P2X4 and P2X7 receptors in native mouse lung - lack of evidence for a direct P2X4-P2X7 receptor interaction.
Sierra-Marquez J, Schaller L, Sassenbach L, Ramírez-Fernández A, Alt P, Rissiek B, Zimmer B, Schredelseker J, Hector J, Stähler T, Koch-Nolte F, Staab-Weijnitz CA, Dietrich A, Kopp R, Nicke A. Sierra-Marquez J, et al. Among authors: nicke a. Front Immunol. 2024 Jun 17;15:1425938. doi: 10.3389/fimmu.2024.1425938. eCollection 2024. Front Immunol. 2024. PMID: 38953020 Free PMC article.
Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs.
Pinto-Espinoza C, Guillou C, Rissiek B, Wilmes M, Javidi E, Schwarz N, Junge M, Haag F, Liaukouskaya N, Wanner N, Nicke A, Stortelers C, Tan YV, Adriouch S, Magnus T, Koch-Nolte F. Pinto-Espinoza C, et al. Among authors: nicke a. Front Pharmacol. 2022 Oct 10;13:1029236. doi: 10.3389/fphar.2022.1029236. eCollection 2022. Front Pharmacol. 2022. PMID: 36299894 Free PMC article.
Animal Models for the Investigation of P2X7 Receptors.
Sluyter R, Adriouch S, Fuller SJ, Nicke A, Sophocleous RA, Watson D. Sluyter R, et al. Among authors: nicke a. Int J Mol Sci. 2023 May 4;24(9):8225. doi: 10.3390/ijms24098225. Int J Mol Sci. 2023. PMID: 37175933 Free PMC article. Review.
Basic Residues at Position 11 of α-Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism.
Haufe Y, Kuruva V, Samanani Z, Lokaj G, Kamnesky G, Shadamarshan P, Shahoei R, Katz D, Sampson JM, Pusch M, Brik A, Nicke A, Leffler AE. Haufe Y, et al. Among authors: nicke a. ACS Chem Neurosci. 2023 Dec 20;14(24):4311-4322. doi: 10.1021/acschemneuro.3c00506. Epub 2023 Dec 5. ACS Chem Neurosci. 2023. PMID: 38051211
The eATP/P2×7R Axis Drives Quantum Dot-Nanoparticle Induced Neutrophil Recruitment in the Pulmonary Microcirculation.
Li C, Liu Q, Han L, Zhang H, Immler R, Rathkolb B, Secklehner J, de Angelis MH, Yildirim AÖ, Zeuschner D, Nicke A, Carlin LM, Sperandio M, Stoeger T, Rehberg M. Li C, et al. Among authors: nicke a. Adv Sci (Weinh). 2024 Dec;11(45):e2404661. doi: 10.1002/advs.202404661. Epub 2024 Oct 4. Adv Sci (Weinh). 2024. PMID: 39364760 Free PMC article.
87 results