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A Novel Multi-organ Male Model of Alcohol-induced Acute-on-chronic Liver Failure Reveals NET-mediated Hepatocellular Death, Which is Prevented by RIPK3 Inhibition.
Ortega-Ribera M, Zhuang Y, Babuta M, Brezani V, Joshi RS, Zsengeller Z, Thevkar Nagesh P, Wang Y, Bronson R, Szabo G. Ortega-Ribera M, et al. Among authors: thevkar nagesh p. Cell Mol Gastroenterol Hepatol. 2024 Dec 20:101446. doi: 10.1016/j.jcmgh.2024.101446. Online ahead of print. Cell Mol Gastroenterol Hepatol. 2024. PMID: 39710168 Free article.
Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone.
Patidar KR, Tu W, Cotter TG, Simonetto DA, Asgharpour A, Jan MY, Tang Q, Yu Y, Li Y, Taiwo M, Thevkar Nagesh P, Dasarathy S, Kamath PS, McClain CJ, Chalasani N, Szabo G, Bataller R, Mitchell M, Mehal WZ, Nagy LE, Shah VH, Gawrieh S, Sanyal AJ; AlcHepNet Investigators. Patidar KR, et al. Among authors: thevkar nagesh p. Hepatology. 2024 Jul 19. doi: 10.1097/HEP.0000000000001019. Online ahead of print. Hepatology. 2024. PMID: 39028887
Neutrophil extracellular traps activate hepatic stellate cells and monocytes via NLRP3 sensing in alcohol-induced acceleration of MASH fibrosis.
Babuta M, Morel C, de Carvalho Ribeiro M, Calenda C, Ortega-Ribera M, Thevkar Nagesh P, Copeland C, Zhuang Y, Wang Y, Cho Y, Joshi R, Brezani V, Hawryluk D, Datta AA, Mehta J, Nasser I, Szabo G. Babuta M, et al. Among authors: thevkar nagesh p. Gut. 2024 Oct 7;73(11):1854-1869. doi: 10.1136/gutjnl-2023-331447. Gut. 2024. PMID: 38777573 Free PMC article.