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145 results

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Page 1
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.
Langer HT, Ramsamooj S, Dantas E, Murthy A, Ahmed M, Ahmed T, Hwang SK, Grover R, Pozovskiy R, Liang RJ, Queiroz AL, Brown JC, White EP, Janowitz T, Goncalves MD. Langer HT, et al. Among authors: goncalves md. Acta Physiol (Oxf). 2024 Aug;240(8):e14167. doi: 10.1111/apha.14167. Epub 2024 May 23. Acta Physiol (Oxf). 2024. PMID: 38779820
Fenofibrate prevents skeletal muscle loss in mice with lung cancer.
Goncalves MD, Hwang SK, Pauli C, Murphy CJ, Cheng Z, Hopkins BD, Wu D, Loughran RM, Emerling BM, Zhang G, Fearon DT, Cantley LC. Goncalves MD, et al. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E743-E752. doi: 10.1073/pnas.1714703115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311302 Free PMC article.
High-fructose corn syrup enhances intestinal tumor growth in mice.
Goncalves MD, Lu C, Tutnauer J, Hartman TE, Hwang SK, Murphy CJ, Pauli C, Morris R, Taylor S, Bosch K, Yang S, Wang Y, Van Riper J, Lekaye HC, Roper J, Kim Y, Chen Q, Gross SS, Rhee KY, Cantley LC, Yun J. Goncalves MD, et al. Science. 2019 Mar 22;363(6433):1345-1349. doi: 10.1126/science.aat8515. Science. 2019. PMID: 30898933 Free PMC article.
GLUT5 (SLC2A5) enables fructose-mediated proliferation independent of ketohexokinase.
Liang RJ, Taylor S, Nahiyaan N, Song J, Murphy CJ, Dantas E, Cheng S, Hsu TW, Ramsamooj S, Grover R, Hwang SK, Ngo B, Cantley LC, Rhee KY, Goncalves MD. Liang RJ, et al. Among authors: goncalves md. Cancer Metab. 2021 Mar 24;9(1):12. doi: 10.1186/s40170-021-00246-9. Cancer Metab. 2021. PMID: 33762003 Free PMC article.
Dietary fructose improves intestinal cell survival and nutrient absorption.
Taylor SR, Ramsamooj S, Liang RJ, Katti A, Pozovskiy R, Vasan N, Hwang SK, Nahiyaan N, Francoeur NJ, Schatoff EM, Johnson JL, Shah MA, Dannenberg AJ, Sebra RP, Dow LE, Cantley LC, Rhee KY, Goncalves MD. Taylor SR, et al. Among authors: goncalves md. Nature. 2021 Sep;597(7875):263-267. doi: 10.1038/s41586-021-03827-2. Epub 2021 Aug 18. Nature. 2021. PMID: 34408323 Free PMC article.
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer.
Queiroz AL, Dantas E, Ramsamooj S, Murthy A, Ahmed M, Zunica ERM, Liang RJ, Murphy J, Holman CD, Bare CJ, Ghahramani G, Wu Z, Cohen DE, Kirwan JP, Cantley LC, Axelrod CL, Goncalves MD. Queiroz AL, et al. Among authors: goncalves md. Nat Commun. 2022 Aug 8;13(1):4633. doi: 10.1038/s41467-022-32135-0. Nat Commun. 2022. PMID: 35941104 Free PMC article.
PDIA3 epitope-driven immune autoreactivity contributes to hepatic damage in type 2 diabetes.
Clement CC, Osan J, Buque A, Nanaware PP, Chang YC, Perino G, Shetty M, Yamazaki T, Tsai WL, Urbanska AM, Calvo-Calle JM, Ramsamooj S, Ramsamooj S, Vergani D, Mieli-Vergani G, Terziroli Beretta-Piccoli B, Gadina M, Montagna C, Goncalves MD, Sallusto F, Galluzzi L, Soni RK, Stern LJ, Santambrogio L. Clement CC, et al. Among authors: goncalves md. Sci Immunol. 2022 Aug 12;7(74):eabl3795. doi: 10.1126/sciimmunol.abl3795. Epub 2022 Aug 19. Sci Immunol. 2022. PMID: 35984892 Free PMC article.
Live cold to grow old? Thermogenesis to fight cancer.
Langer HT, Cantley LC, Goncalves MD. Langer HT, et al. Among authors: goncalves md. Cell Res. 2022 Dec;32(12):1042-1043. doi: 10.1038/s41422-022-00723-w. Cell Res. 2022. PMID: 36085369 Free PMC article. No abstract available.
Cachexia: A systemic consequence of progressive, unresolved disease.
Ferrer M, Anthony TG, Ayres JS, Biffi G, Brown JC, Caan BJ, Cespedes Feliciano EM, Coll AP, Dunne RF, Goncalves MD, Grethlein J, Heymsfield SB, Hui S, Jamal-Hanjani M, Lam JM, Lewis DY, McCandlish D, Mustian KM, O'Rahilly S, Perrimon N, White EP, Janowitz T. Ferrer M, et al. Among authors: goncalves md. Cell. 2023 Apr 27;186(9):1824-1845. doi: 10.1016/j.cell.2023.03.028. Cell. 2023. PMID: 37116469 Free PMC article. Review.
145 results