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341 results

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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy.
Yang C, Geng H, Yang X, Ji S, Liu Z, Feng H, Li Q, Zhang T, Zhang S, Ma X, Zhu C, Xu N, Xia Y, Li Y, Wang H, Yu C, Du S, Miao B, Xu L, Wang H, Cao Y, Li B, Zhu L, Tang X, Zhang H, Zhu C, Huang Z, Leng C, Hu H, Chen X, Yuan S, Jin G, Bernards R, Sun C, Zheng Q, Qin W, Gao Q, Wang C. Yang C, et al. Among authors: bernards r. Cancer Cell. 2024 Dec 9;42(12):2064-2081.e19. doi: 10.1016/j.ccell.2024.10.008. Epub 2024 Nov 7. Cancer Cell. 2024. PMID: 39515328
Addressing the dichotomy between individual and societal approaches to personalised medicine in oncology.
Salgado R, Solit DB, Rimm DL, Bogaerts J, Canetta R, Lively T, Lyerly K, Span PN, Bateman-House A, Makady A, Bergmann L, Nagai S, Smith C, Robson M, Savage M, Voest E, Sweeney C, Lambin P, Thomas M, Harris L, Lacombe D, Massard C; IBCD-Faculty. Salgado R, et al. Eur J Cancer. 2019 Jun;114:128-136. doi: 10.1016/j.ejca.2019.03.025. Epub 2019 May 3. Eur J Cancer. 2019. PMID: 31060925
Deciphering the role of the MALT1-RC3H1 axis in regulating GPX4 protein stability.
Wang J, Liao L, Miao B, Yang B, Li B, Ma X, Fitz A, Wu S, He J, Zhang Q, Ji S, Jin G, Zhang J, Cao Y, Wang H, Qin W, Sun C, Bernards R, Wang C. Wang J, et al. Among authors: bernards r. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2419625121. doi: 10.1073/pnas.2419625121. Epub 2024 Dec 31. Proc Natl Acad Sci U S A. 2025. PMID: 39739814
An antibiotic that mediates immune destruction of senescent cancer cells.
Casagrande Raffi G, Chen J, Feng X, Chen Z, Lieftink C, Deng S, Mo J, Zeng C, Steur M, Wang J, Bleijerveld OB, Hoekman L, van der Wel N, Wang F, Beijersbergen R, Zheng J, Bernards R, Wang L. Casagrande Raffi G, et al. Among authors: bernards r. Proc Natl Acad Sci U S A. 2024 Dec 24;121(52):e2417724121. doi: 10.1073/pnas.2417724121. Epub 2024 Dec 18. Proc Natl Acad Sci U S A. 2024. PMID: 39693343
Efficacy and safety of lenvatinib plus gefitinib in lenvatinib-resistant hepatocellular carcinomas: a prospective, single-arm exploratory trial.
Shi Y, Cui D, Xia L, Shi D, Jin G, Wang S, Lin Y, Tang X, Chi J, Wang T, Li M, Lv Z, Zheng J, Jia Q, Yang W, Sun Z, Yang F, Feng H, Yuan S, Zhou W, Qin W, Bernards R, Jin H, Zhai B. Shi Y, et al. Among authors: bernards r. Signal Transduct Target Ther. 2024 Dec 9;9(1):359. doi: 10.1038/s41392-024-02085-8. Signal Transduct Target Ther. 2024. PMID: 39653700 Free PMC article. Clinical Trial.
341 results