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Inflammation and DKK1-induced AKT activation contribute to endothelial dysfunction following NR2F2 loss.
Dougherty EJ, Chen LY, Awad KS, Ferreyra GA, Demirkale CY, Keshavarz A, Gairhe S, Johnston KA, Hicks ME, Sandler AB, Curran CS, Krack JM, Ding Y, Suffredini AF, Solomon MA, Elinoff JM, Danner RL. Dougherty EJ, et al. Am J Physiol Lung Cell Mol Physiol. 2023 Jun 1;324(6):L783-L798. doi: 10.1152/ajplung.00171.2022. Epub 2023 Apr 11. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37039367 Free PMC article.
Disruption of DLL4/NOTCH1 Causes Dysregulated PPARγ/AKT Signaling in Pulmonary Arterial Hypertension.
Awad KS, Wang S, Dougherty EJ, Keshavarz A, Demirkale CY, Yu ZX, Miller L, Elinoff JM, Danner RL. Awad KS, et al. Among authors: dougherty ej. bioRxiv [Preprint]. 2024 Feb 2:2024.01.31.578230. doi: 10.1101/2024.01.31.578230. bioRxiv. 2024. Update in: Int J Mol Sci. 2024 May 15;25(10):5403. doi: 10.3390/ijms25105403 PMID: 38903104 Free PMC article. Updated. Preprint.
Mineralocorticoid receptor antagonist treatment of established pulmonary arterial hypertension improves interventricular dependence in the SU5416-hypoxia rat model.
Lu M, Chen LY, Gairhe S, Mazer AJ, Anderson SA, Nelson JNH, Noguchi A, Siddique MAH, Dougherty EJ, Zou Y, Johnston KA, Yu ZX, Wang H, Wang S, Sun J, Solomon SB, Vanderpool RR, Solomon MA, Danner RL, Elinoff JM. Lu M, et al. Among authors: dougherty ej. Am J Physiol Lung Cell Mol Physiol. 2022 Mar 1;322(3):L315-L332. doi: 10.1152/ajplung.00238.2021. Epub 2022 Jan 19. Am J Physiol Lung Cell Mol Physiol. 2022. PMID: 35043674 Free PMC article.
Type I interferon activation and endothelial dysfunction in caveolin-1 insufficiency-associated pulmonary arterial hypertension.
Gairhe S, Awad KS, Dougherty EJ, Ferreyra GA, Wang S, Yu ZX, Takeda K, Demirkale CY, Torabi-Parizi P, Austin ED, Elinoff JM, Danner RL. Gairhe S, et al. Among authors: dougherty ej. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2010206118. doi: 10.1073/pnas.2010206118. Proc Natl Acad Sci U S A. 2021. PMID: 33836561 Free PMC article.
23 results