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Page 1
Altered cortical synaptic lipid signaling leads to intermediate phenotypes of mental disorders.
Tüscher O, Muthuraman M, Horstmann JP, Horta G, Radyushkin K, Baumgart J, Sigurdsson T, Endle H, Ji H, Kuhnhäuser P, Götz J, Kepser LJ, Lotze M, Grabe HJ, Völzke H, Leehr EJ, Meinert S, Opel N, Richers S, Stroh A, Daun S, Tittgemeyer M, Uphaus T, Steffen F, Zipp F, Groß J, Groppa S, Dannlowski U, Nitsch R, Vogt J. Tüscher O, et al. Among authors: horta g. Mol Psychiatry. 2024 Nov;29(11):3537-3552. doi: 10.1038/s41380-024-02598-2. Epub 2024 May 28. Mol Psychiatry. 2024. PMID: 38806692 Free PMC article.
Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders.
Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, Distler U, Aoki J, Morris AJ, Geisslinger G, Röper J, Kirischuk S, Luhmann HJ, Radyushkin K, Nitsch R, Vogt J. Thalman C, et al. Among authors: horta g. Mol Psychiatry. 2018 Aug;23(8):1699-1710. doi: 10.1038/s41380-018-0053-1. Epub 2018 May 9. Mol Psychiatry. 2018. PMID: 29743582 Free PMC article.
Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP.
Vogt J, Yang JW, Mobascher A, Cheng J, Li Y, Liu X, Baumgart J, Thalman C, Kirischuk S, Unichenko P, Horta G, Radyushkin K, Stroh A, Richers S, Sahragard N, Distler U, Tenzer S, Qiao L, Lieb K, Tüscher O, Binder H, Ferreiros N, Tegeder I, Morris AJ, Gropa S, Nürnberg P, Toliat MR, Winterer G, Luhmann HJ, Huai J, Nitsch R. Vogt J, et al. Among authors: horta g. EMBO Mol Med. 2016 Jan 1;8(1):25-38. doi: 10.15252/emmm.201505677. EMBO Mol Med. 2016. PMID: 26671989 Free PMC article.
Correction: Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders.
Thalman C, Horta G, Qiao L, Endle H, Tegeder I, Cheng H, Laube G, Sigurdsson T, Hauser MJ, Tenzer S, Distler U, Aoki J, Morris AJ, Geisslinger G, Röper J, Kirischuk S, Luhmann HJ, Radyushkin K, Nitsch R, Vogt J. Thalman C, et al. Among authors: horta g. Mol Psychiatry. 2020 Nov;25(11):3108. doi: 10.1038/s41380-018-0320-1. Mol Psychiatry. 2020. PMID: 30602735 Free PMC article.
AgRP neurons control feeding behaviour at cortical synapses via peripherally derived lysophospholipids.
Endle H, Horta G, Stutz B, Muthuraman M, Tegeder I, Schreiber Y, Snodgrass IF, Gurke R, Liu ZW, Sestan-Pesa M, Radyushkin K, Streu N, Fan W, Baumgart J, Li Y, Kloss F, Groppa S, Opel N, Dannlowski U, Grabe HJ, Zipp F, Rácz B, Horvath TL, Nitsch R, Vogt J. Endle H, et al. Among authors: horta g. Nat Metab. 2022 Jun;4(6):683-692. doi: 10.1038/s42255-022-00589-7. Epub 2022 Jun 27. Nat Metab. 2022. PMID: 35760867 Free PMC article.
PRG-1 Regulates Synaptic Plasticity via Intracellular PP2A/β1-Integrin Signaling.
Liu X, Huai J, Endle H, Schlüter L, Fan W, Li Y, Richers S, Yurugi H, Rajalingam K, Ji H, Cheng H, Rister B, Horta G, Baumgart J, Berger H, Laube G, Schmitt U, Schmeisser MJ, Boeckers TM, Tenzer S, Vlachos A, Deller T, Nitsch R, Vogt J. Liu X, et al. Among authors: horta g. Dev Cell. 2016 Aug 8;38(3):275-90. doi: 10.1016/j.devcel.2016.06.019. Epub 2016 Jul 21. Dev Cell. 2016. PMID: 27453502 Free article.
Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.
Bicker F, Vasic V, Horta G, Ortega F, Nolte H, Kavyanifar A, Keller S, Stankovic ND, Harter PN, Benedito R, Lutz B, Bäuerle T, Hartwig J, Baumgart J, Krüger M, Radyushkin K, Alberi L, Berninger B, Schmidt MHH. Bicker F, et al. Among authors: horta g. Nat Commun. 2017 Jun 28;8:15922. doi: 10.1038/ncomms15922. Nat Commun. 2017. PMID: 28656980 Free PMC article.
The K63 deubiquitinase CYLD modulates autism-like behaviors and hippocampal plasticity by regulating autophagy and mTOR signaling.
Colombo E, Horta G, Roesler MK, Ihbe N, Chhabra S, Radyushkin K, Di Liberto G, Kreutzfeldt M, Schumann S, von Engelhardt J, Merkler D, Behl C, Mittmann T, Clement AM, Waisman A, Schmeisser MJ. Colombo E, et al. Among authors: horta g. Proc Natl Acad Sci U S A. 2021 Nov 23;118(47):e2110755118. doi: 10.1073/pnas.2110755118. Proc Natl Acad Sci U S A. 2021. PMID: 34782467 Free PMC article.
NECAB2 is an endosomal protein important for striatal function.
Bueno D, Narayan Dey P, Schacht T, Wolf C, Wüllner V, Morpurgo E, Rojas-Charry L, Sessinghaus L, Leukel P, Sommer C, Radyushkin K, Florin L, Baumgart J, Stamm P, Daiber A, Horta G, Nardi L, Vasic V, Schmeisser MJ, Hellwig A, Oskamp A, Bauer A, Anand R, Reichert AS, Ritz S, Nocera G, Jacob C, Peper J, Silies M, Frauenknecht KBM, Schäfer MKE, Methner A. Bueno D, et al. Among authors: horta g. Free Radic Biol Med. 2023 Nov 1;208:643-656. doi: 10.1016/j.freeradbiomed.2023.09.003. Epub 2023 Sep 16. Free Radic Biol Med. 2023. PMID: 37722569 Free article.
25 results