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Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination.
Amer-Sarsour F, Falik D, Berdichevsky Y, Kordonsky A, Eid S, Rabinski T, Ishtayeh H, Cohen-Adiv S, Braverman I, Blumen SC, Laviv T, Prag G, Vatine GD, Ashkenazi A. Amer-Sarsour F, et al. Among authors: ashkenazi a. EMBO J. 2024 Jan;43(2):250-276. doi: 10.1038/s44318-023-00018-9. Epub 2024 Jan 2. EMBO J. 2024. PMID: 38177505 Free PMC article.
Ubiquitin Signaling and Degradation of Aggregate-Prone Proteins.
Galves M, Rathi R, Prag G, Ashkenazi A. Galves M, et al. Among authors: ashkenazi a. Trends Biochem Sci. 2019 Oct;44(10):872-884. doi: 10.1016/j.tibs.2019.04.007. Epub 2019 May 9. Trends Biochem Sci. 2019. PMID: 31079890 Review.
Deubiquitylating enzymes in neuronal health and disease.
Amer-Sarsour F, Kordonsky A, Berdichevsky Y, Prag G, Ashkenazi A. Amer-Sarsour F, et al. Among authors: ashkenazi a. Cell Death Dis. 2021 Jan 22;12(1):120. doi: 10.1038/s41419-020-03361-5. Cell Death Dis. 2021. PMID: 33483467 Free PMC article. Review.
VCP/p97 regulates Beclin-1-dependent autophagy initiation.
Hill SM, Wrobel L, Ashkenazi A, Fernandez-Estevez M, Tan K, Bürli RW, Rubinsztein DC. Hill SM, et al. Among authors: ashkenazi a. Nat Chem Biol. 2021 Apr;17(4):448-455. doi: 10.1038/s41589-020-00726-x. Epub 2021 Jan 28. Nat Chem Biol. 2021. PMID: 33510452
TMEM16F regulates pathologic α-synuclein secretion and spread in cellular and mouse models of Parkinson's disease.
Cohen-Adiv S, Amer-Sarsour F, Berdichevsky Y, Boxer E, Goldstein O, Gana-Weisz M, Tripathi U, Rike WA, Prag G, Gurevich T, Giladi N, Stern S, Orr-Urtreger A, Friedmann-Morvinski D, Ashkenazi A. Cohen-Adiv S, et al. Among authors: ashkenazi a. Aging Cell. 2024 Nov 2:e14387. doi: 10.1111/acel.14387. Online ahead of print. Aging Cell. 2024. PMID: 39487963 Free article.
The Nucleolus as a Proteostasis Regulator.
Amer-Sarsour F, Ashkenazi A. Amer-Sarsour F, et al. Among authors: ashkenazi a. Trends Cell Biol. 2019 Nov;29(11):849-851. doi: 10.1016/j.tcb.2019.08.002. Epub 2019 Aug 28. Trends Cell Biol. 2019. PMID: 31473054
Fatty acid balance regulates α-synuclein pathology.
Cohen-Adiv S, Ashkenazi A. Cohen-Adiv S, et al. Among authors: ashkenazi a. Trends Neurosci. 2022 Jun;45(6):417-418. doi: 10.1016/j.tins.2022.03.006. Epub 2022 Apr 1. Trends Neurosci. 2022. PMID: 35379479
566 results