Thomas JR - Search Results

1

Sex specific emergence of trisomic Dyrk1a-related skeletal phenotypes in the development of a Down syndrome mouse model.

LaCombe JM, Sloan K, Thomas JR, Blackwell MP, Crawford I, Wallace JM, Roper RJ. LaCombe JM, et al. Among authors: thomas jr. bioRxiv [Preprint]. 2024 May 26:2024.05.24.595804. doi: 10.1101/2024.05.24.595804. bioRxiv. 2024. Update in: Dis Model Mech. 2024 Sep 1;17(9):dmm050914. doi: 10.1242/dmm.050914 PMID: 38826419 Free PMC article. Updated. Preprint.

2

Differential effects of Epigallocatechin-3-gallate containing supplements on correcting skeletal defects in a Down syndrome mouse model.

Abeysekera I, Thomas J, Georgiadis TM, Berman AG, Hammond MA, Dria KJ, Wallace JM, Roper RJ. Abeysekera I, et al. Mol Nutr Food Res. 2016 Apr;60(4):717-726. doi: 10.1002/mnfr.201500781. Epub 2016 Feb 11. Mol Nutr Food Res. 2016. PMID: 26748562 Free PMC article.

3

Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes.

Stringer M, Abeysekera I, Thomas J, LaCombe J, Stancombe K, Stewart RJ, Dria KJ, Wallace JM, Goodlett CR, Roper RJ. Stringer M, et al. Physiol Behav. 2017 Aug 1;177:230-241. doi: 10.1016/j.physbeh.2017.05.003. Epub 2017 May 3. Physiol Behav. 2017. PMID: 28478033 Free PMC article.

4

Interaction of sexual dimorphism and gene dosage imbalance in skeletal deficits associated with Down syndrome.

Thomas JR, LaCombe J, Long R, Lana-Elola E, Watson-Scales S, Wallace JM, Fisher EMC, Tybulewicz VLJ, Roper RJ. Thomas JR, et al. Bone. 2020 Jul;136:115367. doi: 10.1016/j.bone.2020.115367. Epub 2020 Apr 17. Bone. 2020. PMID: 32305495 Free PMC article.

5

Current Analysis of Skeletal Phenotypes in Down Syndrome.

Thomas JR, Roper RJ. Thomas JR, et al. Curr Osteoporos Rep. 2021 Jun;19(3):338-346. doi: 10.1007/s11914-021-00674-y. Epub 2021 Apr 8. Curr Osteoporos Rep. 2021. PMID: 33830429 Free PMC article. Review.

6

Skeletal Deficits in Male and Female down Syndrome Model Mice Arise Independent of Normalized Dyrk1a Expression in Osteoblasts.

Thomas JR, Sloan K, Cave K, Wallace JM, Roper RJ. Thomas JR, et al. Genes (Basel). 2021 Oct 28;12(11):1729. doi: 10.3390/genes12111729. Genes (Basel). 2021. PMID: 34828335 Free PMC article.

7

Increased dosage and treatment time of Epigallocatechin-3-gallate (EGCG) negatively affects skeletal parameters in normal mice and Down syndrome mouse models.

Jamal R, LaCombe J, Patel R, Blackwell M, Thomas JR, Sloan K, Wallace JM, Roper RJ. Jamal R, et al. Among authors: thomas jr. PLoS One. 2022 Feb 23;17(2):e0264254. doi: 10.1371/journal.pone.0264254. eCollection 2022. PLoS One. 2022. PMID: 35196359 Free PMC article.

8

Genetic dissection of triplicated chromosome 21 orthologs yields varying skeletal traits in Down syndrome model mice.

Sloan K, Thomas J, Blackwell M, Voisard D, Lana-Elola E, Watson-Scales S, Roper DL, Wallace JM, Fisher EMC, Tybulewicz VLJ, Roper RJ. Sloan K, et al. Dis Model Mech. 2023 Apr 1;16(4):dmm049927. doi: 10.1242/dmm.049927. Epub 2023 Apr 26. Dis Model Mech. 2023. PMID: 36939025 Free PMC article.

9

Sex-specific trisomic Dyrk1a-related skeletal phenotypes during development in a Down syndrome model.

LaCombe JM, Sloan K, Thomas JR, Blackwell MP, Crawford I, Bishop F, Wallace JM, Roper RJ. LaCombe JM, et al. Among authors: thomas jr. Dis Model Mech. 2024 Sep 1;17(9):dmm050914. doi: 10.1242/dmm.050914. Epub 2024 Sep 23. Dis Model Mech. 2024. PMID: 39136051 Free PMC article.

10

Respiratory distress, ataxia, and weakness in a ferret (Mustela putorius furo).

Parks S, Roeder M, Magee A, Guarneri L, Carossino M, Jr TNT. Parks S, et al. Among authors: jr tnt. J Am Vet Med Assoc. 2024 Dec 6:1-3. doi: 10.2460/javma.24.08.0561. Online ahead of print. J Am Vet Med Assoc. 2024. PMID: 39642456 No abstract available.

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