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Page 1
A bacterial immunity protein directly senses two disparate phage proteins.
Zhang T, Cepauskas A, Nadieina A, Thureau A, Coppieters 't Wallant K, Martens C, Lim DC, Garcia-Pino A, Laub MT. Zhang T, et al. Among authors: cepauskas a. Nature. 2024 Nov;635(8039):728-735. doi: 10.1038/s41586-024-08039-y. Epub 2024 Oct 16. Nature. 2024. PMID: 39415022 Free PMC article.
Mechanisms of neutralization of toxSAS from toxin-antitoxin modules.
Dominguez-Molina L, Kurata T, Cepauskas A, Echemendia-Blanco D, Zedek S, Talavera-Perez A, Atkinson GC, Hauryliuk V, Garcia-Pino A. Dominguez-Molina L, et al. Among authors: cepauskas a. Nat Chem Biol. 2024 Jun 4. doi: 10.1038/s41589-024-01630-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 38834893
Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin-antitoxin operon.
Dominguez-Molina L, Talavera A, Cepauskas A, Kurata T, Echemendia-Blanco D, Hauryliuk V, Garcia-Pino A. Dominguez-Molina L, et al. Among authors: cepauskas a. Acta Crystallogr F Struct Biol Commun. 2023 Oct 1;79(Pt 10):247-256. doi: 10.1107/S2053230X23007288. Epub 2023 Sep 20. Acta Crystallogr F Struct Biol Commun. 2023. PMID: 37728608 Free PMC article.
Direct activation of a bacterial innate immune system by a viral capsid protein.
Zhang T, Tamman H, Coppieters 't Wallant K, Kurata T, LeRoux M, Srikant S, Brodiazhenko T, Cepauskas A, Talavera A, Martens C, Atkinson GC, Hauryliuk V, Garcia-Pino A, Laub MT. Zhang T, et al. Among authors: cepauskas a. Nature. 2022 Dec;612(7938):132-140. doi: 10.1038/s41586-022-05444-z. Epub 2022 Nov 16. Nature. 2022. PMID: 36385533 Free PMC article.
A widespread toxin-antitoxin system exploiting growth control via alarmone signaling.
Jimmy S, Saha CK, Kurata T, Stavropoulos C, Oliveira SRA, Koh A, Cepauskas A, Takada H, Rejman D, Tenson T, Strahl H, Garcia-Pino A, Hauryliuk V, Atkinson GC. Jimmy S, et al. Among authors: cepauskas a. Proc Natl Acad Sci U S A. 2020 May 12;117(19):10500-10510. doi: 10.1073/pnas.1916617117. Epub 2020 Apr 28. Proc Natl Acad Sci U S A. 2020. PMID: 32345719 Free PMC article.