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Page 1
mRNA-encoded Cas13 can be used to treat dengue infections in mice.
Basu M, Zurla C, Auroni TT, Vanover D, Chaves LCS, Sadhwani H, Pathak H, Basu R, Beyersdorf JP, Amuda OO, Elsharkawy A, Mosur V, Arthur RA, Claussen H, Sasser LE, Wroe JA, Peck HE, Kumar M, Brinton MA, Santangelo PJ. Basu M, et al. Among authors: chaves lcs. Nat Microbiol. 2024 Aug;9(8):2160-2172. doi: 10.1038/s41564-024-01726-6. Epub 2024 Jun 5. Nat Microbiol. 2024. PMID: 38839984
Nebulized mRNA-Encoded Antibodies Protect Hamsters from SARS-CoV-2 Infection.
Vanover D, Zurla C, Peck HE, Orr-Burks N, Joo JY, Murray J, Holladay N, Hobbs RA, Jung Y, Chaves LCS, Rotolo L, Lifland AW, Olivier AK, Li D, Saunders KO, Sempowski GD, Crowe JE Jr, Haynes BF, Lafontaine ER, Hogan RJ, Santangelo PJ. Vanover D, et al. Among authors: chaves lcs. Adv Sci (Weinh). 2022 Dec;9(34):e2202771. doi: 10.1002/advs.202202771. Epub 2022 Oct 31. Adv Sci (Weinh). 2022. PMID: 36316224 Free PMC article.
Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung.
Rotolo L, Vanover D, Bruno NC, Peck HE, Zurla C, Murray J, Noel RK, O'Farrell L, Araínga M, Orr-Burks N, Joo JY, Chaves LCS, Jung Y, Beyersdorf J, Gumber S, Guerrero-Ferreira R, Cornejo S, Thoresen M, Olivier AK, Kuo KM, Gumbart JC, Woolums AR, Villinger F, Lafontaine ER, Hogan RJ, Finn MG, Santangelo PJ. Rotolo L, et al. Among authors: chaves lcs. Nat Mater. 2023 Mar;22(3):369-379. doi: 10.1038/s41563-022-01404-0. Epub 2022 Nov 28. Nat Mater. 2023. PMID: 36443576
mRNA-encoded Cas13 treatment of Influenza via site-specific degradation of genomic RNA.
Chaves LCS, Orr-Burks N, Vanover D, Mosur VV, Hosking SR, Kumar E K P, Jeong H, Jung Y, Assumpção JAF, Peck HE, Nelson SL, Burke KN, Garrison MA, Arthur RA, Claussen H, Heaton NS, Lafontaine ER, Hogan RJ, Zurla C, Santangelo PJ. Chaves LCS, et al. PLoS Pathog. 2024 Jul 5;20(7):e1012345. doi: 10.1371/journal.ppat.1012345. eCollection 2024 Jul. PLoS Pathog. 2024. PMID: 38968329 Free PMC article.
Vaccines against Emerging and Neglected Infectious Diseases: An Overview.
Vuitika L, Prates-Syed WA, Silva JDQ, Crema KP, Côrtes N, Lira A, Lima JBM, Camara NOS, Schimke LF, Cabral-Marques O, Sadraeian M, Chaves LCS, Cabral-Miranda G. Vuitika L, et al. Among authors: chaves lcs. Vaccines (Basel). 2022 Aug 25;10(9):1385. doi: 10.3390/vaccines10091385. Vaccines (Basel). 2022. PMID: 36146463 Free PMC article. Review.
VLP-Based COVID-19 Vaccines: An Adaptable Technology against the Threat of New Variants.
Prates-Syed WA, Chaves LCS, Crema KP, Vuitika L, Lira A, Côrtes N, Kersten V, Guimarães FEG, Sadraeian M, Barroso da Silva FL, Cabral-Marques O, Barbuto JAM, Russo M, Câmara NOS, Cabral-Miranda G. Prates-Syed WA, et al. Among authors: chaves lcs. Vaccines (Basel). 2021 Nov 30;9(12):1409. doi: 10.3390/vaccines9121409. Vaccines (Basel). 2021. PMID: 34960155 Free PMC article. Review.