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Page 1
Comparative small molecule screening of primary human acute leukemias, engineered human leukemia and leukemia cell lines.
Safa-Tahar-Henni S, Páez Martinez K, Gress V, Esparza N, Roques É, Bonnet-Magnaval F, Bilodeau M, Gagné V, Bresson E, Cardin S, El-Hachem N, Iasenza I, Alzial G, Boivin I, Nakamichi N, Soufflet AC, Mirela Pascariu C, Duchaine J, Mathien S, Bonneil É, Eppert K, Marinier A, Sauvageau G, Deblois G, Thibault P, Hébert J, Eaves CJ, Cellot S, Barabé F, Wilhelm BT. Safa-Tahar-Henni S, et al. Among authors: el hachem n. Leukemia. 2025 Jan;39(1):29-41. doi: 10.1038/s41375-024-02400-w. Epub 2024 Oct 29. Leukemia. 2025. PMID: 39472547 Free PMC article.
Body appreciation is associated with optimism/pessimism in patients with chronic kidney disease: Results from a cross-sectional study and validation of the Arabic version of the Optimism-Pessimism Short Scale-2.
Hajj-Moussa M, El Hachem N, El Sebaaly Z, Moubarak P, Kahwagi RM, Malaeb D, Hallit R, El Khatib S, Hallit S, Obeid S, Fekih-Romdhane F. Hajj-Moussa M, et al. Among authors: el hachem n. PLoS One. 2024 Sep 6;19(9):e0306262. doi: 10.1371/journal.pone.0306262. eCollection 2024. PLoS One. 2024. PMID: 39240857 Free PMC article.
Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis.
Wathieu C, Lavergne A, Xu X, Rolot M, Nemazanyy I, Shostak K, El Hachem N, Maurizy C, Leemans C, Close P, Nguyen L, Desmet C, Tielens S, Dewals BG, Chariot A. Wathieu C, et al. Among authors: el hachem n. EMBO J. 2024 Sep;43(18):3916-3947. doi: 10.1038/s44318-024-00184-4. Epub 2024 Jul 31. EMBO J. 2024. PMID: 39085648 Free PMC article.
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma.
El-Hachem N, Leclercq M, Susaeta Ruiz M, Vanleyssem R, Shostak K, Körner PR, Capron C, Martin-Morales L, Roncarati P, Lavergne A, Blomme A, Turchetto S, Goffin E, Thandapani P, Tarassov I, Nguyen L, Pirotte B, Chariot A, Marine JC, Herfs M, Rapino F, Agami R, Close P. El-Hachem N, et al. Nat Cell Biol. 2024 Jul;26(7):1154-1164. doi: 10.1038/s41556-024-01439-2. Epub 2024 Jun 7. Nat Cell Biol. 2024. PMID: 38849541 Free PMC article.
A1-reprogrammed mesenchymal stromal cells prime potent antitumoral responses.
Gonçalves MP, Farah R, Bikorimana JP, Abusarah J, El-Hachem N, Saad W, Talbot S, Stanga D, Beaudoin S, Plouffe S, Rafei M. Gonçalves MP, et al. Among authors: el hachem n. iScience. 2024 Feb 17;27(3):109248. doi: 10.1016/j.isci.2024.109248. eCollection 2024 Mar 15. iScience. 2024. PMID: 38433914 Free PMC article.
CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard É, Thibault P, Bonneil É, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith MA, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm BT, Cellot S. Gress V, et al. Among authors: el hachem n. Blood Adv. 2024 Jan 9;8(1):112-129. doi: 10.1182/bloodadvances.2022008899. Blood Adv. 2024. PMID: 37729615 Free PMC article.
Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as a therapeutic strategy in CLL.
Largeot A, Klapp V, Viry E, Gonder S, Fernandez Botana I, Blomme A, Benzarti M, Pierson S, Duculty C, Marttila P, Wierz M, Gargiulo E, Pagano G, An N, El Hachem N, Perez Hernandez D, Chakraborty S, Ysebaert L, François JH, Cortez Clemente S, Berchem G, Efremov DG, Dittmar G, Szpakowska M, Chevigné A, Nazarov PV, Helleday T, Close P, Meiser J, Stamatopoulos B, Désaubry L, Paggetti J, Moussay E. Largeot A, et al. Among authors: el hachem n. Blood. 2023 Jun 29;141(26):3166-3183. doi: 10.1182/blood.2022017839. Blood. 2023. PMID: 37084385 Free PMC article.
67 results