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RET overexpression leads to increased brain metastatic competency in luminal breast cancer.
Jagust P, Powell AM, Ola M, Watson L, de Pablos-Aragoneses A, García-Gómez P, Fallon R, Bane F, Heiland M, Morris G, Cavanagh B, McGrath J, Ottaviani D, Hegarty A, Cocchiglia S, Sweeney KJ, MacNally S, Brett FM, Cryan J, Beausang A, Morris P, Valiente M, Hill ADK, Varešlija D, Young LS. Jagust P, et al. Among authors: fallon r. J Natl Cancer Inst. 2024 Oct 1;116(10):1632-1644. doi: 10.1093/jnci/djae091. J Natl Cancer Inst. 2024. PMID: 38852945 Free PMC article.
Neoadjuvant HER2 inhibition induces ESR1 DNA methylation alterations resulting in clinically relevant ER expression changes in breast cancers.
Dowling GP, Daly GR, Hegarty A, Flanagan M, Ola M, Fallon R, Cocchiglia S, Singh V, Sheehan KM, Bane F, McGrath J, Watson L, Hembrecht S, Hennessy B, Morris PG, Hill ADK, Varešlija D, Young LS. Dowling GP, et al. Among authors: fallon r. Cancer Commun (Lond). 2024 Dec 15. doi: 10.1002/cac2.12640. Online ahead of print. Cancer Commun (Lond). 2024. PMID: 39676516 No abstract available.
Serine and glycine physiology reversibly modulate retinal and peripheral nerve function.
Lim EW, Fallon RJ, Bates C, Ideguchi Y, Nagasaki T, Handzlik MK, Joulia E, Bonelli R, Green CR, Ansell BRE, Kitano M, Polis I, Roberts AJ, Furuya S, Allikmets R, Wallace M, Friedlander M, Metallo CM, Gantner ML. Lim EW, et al. Among authors: fallon rj. Cell Metab. 2024 Oct 1;36(10):2315-2328.e6. doi: 10.1016/j.cmet.2024.07.021. Epub 2024 Aug 26. Cell Metab. 2024. PMID: 39191258 Free article.
iPSC-derived retinal pigmented epithelial cells from patients with macular telangiectasia show decreased mitochondrial function.
Eade KT, Ansell BRE, Giles S, Fallon R, Harkins-Perry S, Nagasaki T, Tzaridis S, Wallace M, Mills EA, Farashi S, Johnson A, Sauer L, Hart B, Diaz-Rubio ME, Bahlo M, Metallo C, Allikmets R, Gantner ML, Bernstein PS, Friedlander M. Eade KT, et al. Among authors: fallon r. J Clin Invest. 2023 May 1;133(9):e163771. doi: 10.1172/JCI163771. J Clin Invest. 2023. PMID: 37115691 Free PMC article.
Insulin-regulated serine and lipid metabolism drive peripheral neuropathy.
Handzlik MK, Gengatharan JM, Frizzi KE, McGregor GH, Martino C, Rahman G, Gonzalez A, Moreno AM, Green CR, Guernsey LS, Lin T, Tseng P, Ideguchi Y, Fallon RJ, Chaix A, Panda S, Mali P, Wallace M, Knight R, Gantner ML, Calcutt NA, Metallo CM. Handzlik MK, et al. Among authors: fallon rj. Nature. 2023 Feb;614(7946):118-124. doi: 10.1038/s41586-022-05637-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697822 Free PMC article.
Triglyceride Lowering with Pemafibrate to Reduce Cardiovascular Risk.
Das Pradhan A, Glynn RJ, Fruchart JC, MacFadyen JG, Zaharris ES, Everett BM, Campbell SE, Oshima R, Amarenco P, Blom DJ, Brinton EA, Eckel RH, Elam MB, Felicio JS, Ginsberg HN, Goudev A, Ishibashi S, Joseph J, Kodama T, Koenig W, Leiter LA, Lorenzatti AJ, Mankovsky B, Marx N, Nordestgaard BG, Páll D, Ray KK, Santos RD, Soran H, Susekov A, Tendera M, Yokote K, Paynter NP, Buring JE, Libby P, Ridker PM; PROMINENT Investigators. Das Pradhan A, et al. N Engl J Med. 2022 Nov 24;387(21):1923-1934. doi: 10.1056/NEJMoa2210645. Epub 2022 Nov 5. N Engl J Med. 2022. PMID: 36342113 Clinical Trial.
There's a New Sheriff in Town: When Enterprise IT Takes Over Imaging IT.
Dennison DK, Coleman RM, Fallon R, Toland M, Kennedy RSL, Tomlin B. Dennison DK, et al. Among authors: fallon r. J Digit Imaging. 2021 Aug;34(4):974-985. doi: 10.1007/s10278-021-00485-8. Epub 2021 Jul 13. J Digit Imaging. 2021. PMID: 34255217 Free PMC article.
280 results