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26 results

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Page 1
Large-scale single-nuclei profiling identifies role for ATRNL1 in atrial fibrillation.
Hill MC, Simonson B, Roselli C, Xiao L, Herndon CN, Chaffin M, Mantineo H, Atwa O, Bhasin H, Guedira Y, Bedi KC Jr, Margulies KB, Klattenhoff CA, Tucker NR, Ellinor PT. Hill MC, et al. Among authors: bedi kc jr. Nat Commun. 2024 Nov 19;15(1):10002. doi: 10.1038/s41467-024-54296-w. Nat Commun. 2024. PMID: 39562555 Free PMC article.
Endogenous adenine is a potential driver of the cardiovascular-kidney-metabolic syndrome.
Tamayo I, Lee HJ, Aslam MI, Liu JJ, Ragi N, Karanam V, Maity S, Saliba A, Treviño E, Zheng H, Lim SC, Lanzer JD, Bjornstad P, Tuttle K, Bedi KC Jr, Margulies KB, Ramachandran V, Abdel-Latif A, Saez-Rodriguez J, Iyengar R, Bopassa JC, Sharma K. Tamayo I, et al. Among authors: bedi kc jr. medRxiv [Preprint]. 2024 Aug 20:2024.08.19.24312277. doi: 10.1101/2024.08.19.24312277. medRxiv. 2024. PMID: 39228698 Free PMC article. Preprint.
Nuclear ATP-citrate lyase regulates chromatin-dependent activation and maintenance of the myofibroblast gene program.
Lazaropoulos MP, Gibb AA, Chapski DJ, Nair AA, Reiter AN, Roy R, Eaton DM, Bedi KC Jr, Margulies KB, Wellen KE, Estarás C, Vondriska TM, Elrod JW. Lazaropoulos MP, et al. Among authors: bedi kc jr. Nat Cardiovasc Res. 2024 Jul;3(7):869-882. doi: 10.1038/s44161-024-00502-3. Epub 2024 Jul 5. Nat Cardiovasc Res. 2024. PMID: 39196175 Free PMC article.
Myocardial ultrastructure of human heart failure with preserved ejection fraction.
Meddeb M, Koleini N, Binek A, Keykhaei M, Darehgazani R, Kwon S, Aboaf C, Margulies KB, Bedi KC Jr, Lehar M, Sharma K, Hahn VS, Van Eyk JE, Drachenberg CI, Kass DA. Meddeb M, et al. Among authors: bedi kc jr. Nat Cardiovasc Res. 2024 Aug;3(8):907-914. doi: 10.1038/s44161-024-00516-x. Epub 2024 Jul 25. Nat Cardiovasc Res. 2024. PMID: 39196036
Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction.
Eaton DM, Lee BW, Caporizzo MA, Iyengar A, Chen CY, Uchida K, Marcellin G, Lannay Y, Vite A, Bedi KC Jr, Brady CF, Smolyak JN, Meldrum D, Dominic J, Weingarten N, Patel M, Belec A, Hached K, Atluri P, Van Der Laan S, Prosser BL, Margulies KB. Eaton DM, et al. Among authors: bedi kc jr. Sci Transl Med. 2024 Jul 17;16(756):eadm8842. doi: 10.1126/scitranslmed.adm8842. Epub 2024 Jul 17. Sci Transl Med. 2024. PMID: 39018366
Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy.
Nollet EE, Schuldt M, Sequeira V, Binek A, Pham TV, Schoonvelde SAC, Jansen M, Schomakers BV, van Weeghel M, Vaz FM, Houtkooper RH, Van Eyk JE, Jimenez CR, Michels M, Bedi KC Jr, Margulies KB, Dos Remedios CG, Kuster DWD, van der Velden J. Nollet EE, et al. Among authors: bedi kc jr. Circ Genom Precis Med. 2024 Jun;17(3):e004369. doi: 10.1161/CIRCGEN.123.004369. Epub 2024 Jun 10. Circ Genom Precis Med. 2024. PMID: 38853772 Free PMC article.
Adult human cardiomyocyte mechanics in osteogenesis imperfecta.
Lee BW, Caporizzo MA, Chen CY, Bedi KC Jr, Peyster EG, Prosser BL, Margulies KB, Vite A. Lee BW, et al. Among authors: bedi kc jr. Am J Physiol Heart Circ Physiol. 2023 Oct 1;325(4):H814-H821. doi: 10.1152/ajpheart.00391.2023. Epub 2023 Aug 11. Am J Physiol Heart Circ Physiol. 2023. PMID: 37566108 Free PMC article.
Myocardial Metabolomics of Human Heart Failure With Preserved Ejection Fraction.
Hahn VS, Petucci C, Kim MS, Bedi KC Jr, Wang H, Mishra S, Koleini N, Yoo EJ, Margulies KB, Arany Z, Kelly DP, Kass DA, Sharma K. Hahn VS, et al. Among authors: bedi kc jr. Circulation. 2023 Apr 11;147(15):1147-1161. doi: 10.1161/CIRCULATIONAHA.122.061846. Epub 2023 Mar 1. Circulation. 2023. PMID: 36856044 Free PMC article.
Single-nucleus RNA sequencing in ischemic cardiomyopathy reveals common transcriptional profile underlying end-stage heart failure.
Simonson B, Chaffin M, Hill MC, Atwa O, Guedira Y, Bhasin H, Hall AW, Hayat S, Baumgart S, Bedi KC Jr, Margulies KB, Klattenhoff CA, Ellinor PT. Simonson B, et al. Among authors: bedi kc jr. Cell Rep. 2023 Feb 28;42(2):112086. doi: 10.1016/j.celrep.2023.112086. Epub 2023 Feb 14. Cell Rep. 2023. PMID: 36790929 Free PMC article.
26 results