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371 results

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Integrating Clinical Phenotype With Multiomics Analyses of Human Cardiac Tissue Unveils Divergent Metabolic Remodeling in Genotype-Positive and Genotype-Negative Patients With Hypertrophic Cardiomyopathy.
Nollet EE, Schuldt M, Sequeira V, Binek A, Pham TV, Schoonvelde SAC, Jansen M, Schomakers BV, van Weeghel M, Vaz FM, Houtkooper RH, Van Eyk JE, Jimenez CR, Michels M, Bedi KC Jr, Margulies KB, Dos Remedios CG, Kuster DWD, van der Velden J. Nollet EE, et al. Among authors: van weeghel m, van eyk je, van der velden j. Circ Genom Precis Med. 2024 Jun;17(3):e004369. doi: 10.1161/CIRCGEN.123.004369. Epub 2024 Jun 10. Circ Genom Precis Med. 2024. PMID: 38853772 Free PMC article.
Genomics, proteomics and bioinformatics of human heart failure.
Dos Remedios CG, Liew CC, Allen PD, Winslow RL, Van Eyk JE, Dunn MJ. Dos Remedios CG, et al. Among authors: van eyk je. J Muscle Res Cell Motil. 2003;24(4-6):251-60. doi: 10.1023/a:1025433721505. J Muscle Res Cell Motil. 2003. PMID: 14620738 Free PMC article. Review.
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, van der Velden J, Stienen GJ. Narolska NA, et al. Among authors: van eyk je, van der velden j. Circ Res. 2006 Oct 27;99(9):1012-20. doi: 10.1161/01.RES.0000248753.30340.af. Epub 2006 Oct 5. Circ Res. 2006. PMID: 17023673
PKCα-specific phosphorylation of the troponin complex in human myocardium: a functional and proteomics analysis.
Kooij V, Zhang P, Piersma SR, Sequeira V, Boontje NM, Wijnker PJ, Jiménez CR, Jaquet KE, dos Remedios C, Murphy AM, Van Eyk JE, van der Velden J, Stienen GJ. Kooij V, et al. Among authors: van eyk je, van der velden j. PLoS One. 2013 Oct 7;8(10):e74847. doi: 10.1371/journal.pone.0074847. eCollection 2013. PLoS One. 2013. PMID: 24116014 Free PMC article.
A novel phosphorylation site, Serine 199, in the C-terminus of cardiac troponin I regulates calcium sensitivity and susceptibility to calpain-induced proteolysis.
Wijnker PJ, Li Y, Zhang P, Foster DB, dos Remedios C, Van Eyk JE, Stienen GJ, Murphy AM, van der Velden J. Wijnker PJ, et al. Among authors: van eyk je, van der velden j. J Mol Cell Cardiol. 2015 May;82:93-103. doi: 10.1016/j.yjmcc.2015.03.006. Epub 2015 Mar 11. J Mol Cell Cardiol. 2015. PMID: 25771144 Free PMC article.
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.
Lee DI, Zhu G, Sasaki T, Cho GS, Hamdani N, Holewinski R, Jo SH, Danner T, Zhang M, Rainer PP, Bedja D, Kirk JA, Ranek MJ, Dostmann WR, Kwon C, Margulies KB, Van Eyk JE, Paulus WJ, Takimoto E, Kass DA. Lee DI, et al. Among authors: van eyk je. Nature. 2015 Mar 26;519(7544):472-6. doi: 10.1038/nature14332. Epub 2015 Mar 18. Nature. 2015. PMID: 25799991 Free PMC article.
Discovery Proteomics for COVID-19: Where We Are Now.
McArdle A, Washington KE, Chazarin Orgel B, Binek A, Manalo DM, Rivas A, Ayres M, Pandey R, Phebus C, Raedschelders K, Fert-Bober J, Van Eyk JE. McArdle A, et al. Among authors: van eyk je. J Proteome Res. 2021 Oct 1;20(10):4627-4639. doi: 10.1021/acs.jproteome.1c00475. Epub 2021 Sep 22. J Proteome Res. 2021. PMID: 34550702 Free PMC article. Review.
371 results