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Page 1
Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets.
Agoro R, Myslinski J, Marambio YG, Janosevic D, Jennings KN, Liu S, Hibbard LM, Fang F, Ni P, Noonan ML, Solis E, Chu X, Wang Y, Dagher PC, Liu Y, Wan J, Hato T, White KE. Agoro R, et al. Among authors: dagher pc. bioRxiv [Preprint]. 2024 May 28:2024.05.24.595014. doi: 10.1101/2024.05.24.595014. bioRxiv. 2024. PMID: 38853876 Free PMC article. Preprint.
The chromatin landscape of healthy and injured cell types in the human kidney.
Gisch DL, Brennan M, Lake BB, Basta J, Keller M, Ferreira RM, Akilesh S, Ghag R, Lu C, Cheng YH, Collins KS, Parikh SV, Rovin BH, Robbins L, Conklin KY, Diep D, Zhang B, Knoten A, Barwinska D, Asghari M, Sabo AR, Ferkowicz MJ, Sutton TA, Kelly KJ, Boer IH, Rosas SE, Kiryluk K, Hodgin JB, Alakwaa F, Jefferson N, Gaut JP, Gehlenborg N, Phillips CL, El-Achkar TM, Dagher PC, Hato T, Zhang K, Himmelfarb J, Kretzler M, Mollah S; Kidney Precision Medicine Project (KPMP); Jain S, Rauchman M, Eadon MT. Gisch DL, et al. Among authors: dagher pc. bioRxiv [Preprint]. 2023 Jun 8:2023.06.07.543965. doi: 10.1101/2023.06.07.543965. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 10;15(1):433. doi: 10.1038/s41467-023-44467-6 PMID: 37333123 Free PMC article. Updated. Preprint.
Integration of spatial multiplexed protein imaging and transcriptomics in the human kidney tracks the regenerative potential timeline of proximal tubules.
Asghari M, Sabo AR, Barwinska D, Ferreira RM, Ferkowicz M, Bowen WS, Cheng YH, Gisch DL, Gulbronson C, Phillips CL, Kelly KJ, Sutton TA, Williams JC, Vazquez M, O'Toole J, Palevsky P, Rosas SE, Waikar SS, Kiryluk K, Parikh C, Hodgins J, Sarder P, De Boer IH, Himmelfarb J, Kretzler M; Kidney Precision Medicine Project; Jain S, Eadon MT, Winfree S, El-Achkar TM, Dagher PC. Asghari M, et al. Among authors: dagher pc. bioRxiv [Preprint]. 2024 Dec 2:2024.11.26.625544. doi: 10.1101/2024.11.26.625544. bioRxiv. 2024. PMID: 39677736 Free PMC article. Preprint.
The chromatin landscape of healthy and injured cell types in the human kidney.
Gisch DL, Brennan M, Lake BB, Basta J, Keller MS, Melo Ferreira R, Akilesh S, Ghag R, Lu C, Cheng YH, Collins KS, Parikh SV, Rovin BH, Robbins L, Stout L, Conklin KY, Diep D, Zhang B, Knoten A, Barwinska D, Asghari M, Sabo AR, Ferkowicz MJ, Sutton TA, Kelly KJ, De Boer IH, Rosas SE, Kiryluk K, Hodgin JB, Alakwaa F, Winfree S, Jefferson N, Türkmen A, Gaut JP, Gehlenborg N, Phillips CL, El-Achkar TM, Dagher PC, Hato T, Zhang K, Himmelfarb J, Kretzler M, Mollah S; Kidney Precision Medicine Project (KPMP); Jain S, Rauchman M, Eadon MT. Gisch DL, et al. Among authors: dagher pc. Nat Commun. 2024 Jan 10;15(1):433. doi: 10.1038/s41467-023-44467-6. Nat Commun. 2024. PMID: 38199997 Free PMC article.
A MEF2C transcription factor network regulates proliferation of glomerular endothelial cells in diabetic kidney disease.
Ferreira RM, Gisch DL, Phillips CL, Cheng YH, Asthana M, Lake BB, Bowen WS, Fang F, Asghari M, Sabo A, Barwinska D, Ferkowicz MJ, Toto RD, Sedor JR, Rosas SE, Bjornstad P, Hodgin JB, Alpers CE, Sarder P, Himmelfarb J, Schaub JA, Nair V, Winfree S, Sutton TA, Kelly KJ; Kidney Precision Medicine Project; Kretzler M, Jain S, El-Achkar TM, Dagher PC, Eadon MT. Ferreira RM, et al. Among authors: dagher pc. bioRxiv [Preprint]. 2024 Dec 31:2024.09.27.615250. doi: 10.1101/2024.09.27.615250. bioRxiv. 2024. PMID: 39803522 Free PMC article. Preprint.
miRNA and mRNA Signatures in Human Acute Kidney Injury Tissue.
Janosevic D, De Luca T, Melo Ferreira R, Gisch DL, Cheng YH, Hato T, Luo J, Yang Y, Hodgin JB, Phillips CL, Dagher PC; Kidney Precision Medicine Project; Eadon MT. Janosevic D, et al. Among authors: dagher pc. Am J Pathol. 2025 Jan;195(1):102-114. doi: 10.1016/j.ajpath.2024.08.013. Epub 2024 Sep 25. Am J Pathol. 2025. PMID: 39332675
Inflammation primes the kidney for recovery by activating AZIN1 A-to-I editing.
Heruye S, Myslinski J, Zeng C, Zollman A, Makino S, Nanamatsu A, Mir Q, Janga SC, Doud EH, Eadon MT, Maier B, Hamada M, Tran TM, Dagher PC, Hato T. Heruye S, et al. Among authors: dagher pc. bioRxiv [Preprint]. 2023 Nov 9:2023.11.09.566426. doi: 10.1101/2023.11.09.566426. bioRxiv. 2023. Update in: J Clin Invest. 2024 Sep 3;134(17):e180117. doi: 10.1172/JCI180117 PMID: 37986799 Free PMC article. Updated. Preprint.
Participant Experience with Protocol Research Kidney Biopsies in the Kidney Precision Medicine Project.
Victoria-Castro AM, Corona-Villalobos CP, Xu AY, Onul I, Huynh C, Chen SW, Ugwuowo U, Sarkisova N, Dighe AL, Blank KN, Blanc VM, Rose MP, Himmelfarb J, de Boer IH, Tuttle KR, Roberts GV; Kidney Precision Medicine Project. Victoria-Castro AM, et al. Clin J Am Soc Nephrol. 2024 Feb 1;19(2):202-212. doi: 10.2215/CJN.0000000000000334. Epub 2023 Oct 23. Clin J Am Soc Nephrol. 2024. PMID: 37871973
90 results