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Page 1
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Kim J, Tierney BT, Overbey EG, Dantas E, Fuentealba M, Park J, Narayanan SA, Wu F, Najjar D, Chin CR, Meydan C, Loy C, Mathyk B, Klotz R, Ortiz V, Nguyen K, Ryon KA, Damle N, Houerbi N, Patras LI, Schanzer N, Hutchinson GA, Foox J, Bhattacharya C, Mackay M, Afshin EE, Hirschberg JW, Kleinman AS, Schmidt JC, Schmidt CM, Schmidt MA, Beheshti A, Matei I, Lyden D, Mullane S, Asadi A, Lenz JS, Mzava O, Yu M, Ganesan S, De Vlaminck I, Melnick AM, Barisic D, Winer DA, Zwart SR, Crucian BE, Smith SM, Mateus J, Furman D, Mason CE. Kim J, et al. Among authors: furman d. Nat Commun. 2024 Jun 11;15(1):4954. doi: 10.1038/s41467-024-49211-2. Nat Commun. 2024. PMID: 38862516 Free PMC article.
SARS-CoV-2, COVID-19 and the Ageing Immune System.
Bartleson JM, Radenkovic D, Covarrubias AJ, Furman D, Winer DA, Verdin E. Bartleson JM, et al. Among authors: furman d. Nat Aging. 2021 Sep;1(9):769-782. doi: 10.1038/s43587-021-00114-7. Epub 2021 Sep 14. Nat Aging. 2021. PMID: 34746804 Free PMC article.
A second space age spanning omics, platforms and medicine across orbits.
Mason CE, Green J, Adamopoulos KI, Afshin EE, Baechle JJ, Basner M, Bailey SM, Bielski L, Borg J, Borg J, Broddrick JT, Burke M, Caicedo A, Castañeda V, Chatterjee S, Chin CR, Church G, Costes SV, De Vlaminck I, Desai RI, Dhir R, Diaz JE, Etlin SM, Feinstein Z, Furman D, Garcia-Medina JS, Garrett-Bakelman F, Giacomello S, Gupta A, Hassanin A, Houerbi N, Irby I, Javorsky E, Jirak P, Jones CW, Kamal KY, Kangas BD, Karouia F, Kim J, Kim JH, Kleinman AS, Lam T, Lawler JM, Lee JA, Limoli CL, Lucaci A, MacKay M, McDonald JT, Melnick AM, Meydan C, Mieczkowski J, Muratani M, Najjar D, Othman MA, Overbey EG, Paar V, Park J, Paul AM, Perdyan A, Proszynski J, Reynolds RJ, Ronca AE, Rubins K, Ryon KA, Sanders LM, Glowe PS, Shevde Y, Schmidt MA, Scott RT, Shirah B, Sienkiewicz K, Sierra MA, Siew K, Theriot CA, Tierney BT, Venkateswaran K, Hirschberg JW, Walsh SB, Walter C, Winer DA, Yu M, Zea L, Mateus J, Beheshti A. Mason CE, et al. Among authors: furman d. Nature. 2024 Aug;632(8027):995-1008. doi: 10.1038/s41586-024-07586-8. Epub 2024 Jun 11. Nature. 2024. PMID: 38862027 Review.
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank.
Overbey EG, Kim J, Tierney BT, Park J, Houerbi N, Lucaci AG, Garcia Medina S, Damle N, Najjar D, Grigorev K, Afshin EE, Ryon KA, Sienkiewicz K, Patras L, Klotz R, Ortiz V, MacKay M, Schweickart A, Chin CR, Sierra MA, Valenzuela MF, Dantas E, Nelson TM, Cekanaviciute E, Deards G, Foox J, Narayanan SA, Schmidt CM, Schmidt MA, Schmidt JC, Mullane S, Tigchelaar SS, Levitte S, Westover C, Bhattacharya C, Lucotti S, Wain Hirschberg J, Proszynski J, Burke M, Kleinman AS, Butler DJ, Loy C, Mzava O, Lenz J, Paul D, Mozsary C, Sanders LM, Taylor LE, Patel CO, Khan SA, Suhail Mohamad M, Byhaqui SGA, Aslam B, Gajadhar AS, Williamson L, Tandel P, Yang Q, Chu J, Benz RW, Siddiqui A, Hornburg D, Blease K, Moreno J, Boddicker A, Zhao J, Lajoie B, Scott RT, Gilbert RR, Lai Polo SH, Altomare A, Kruglyak S, Levy S, Ariyapala I, Beer J, Zhang B, Hudson BM, Rininger A, Church SE, Beheshti A, Church GM, Smith SM, Crucian BE, Zwart SR, Matei I, Lyden DC, Garrett-Bakelman F, Krumsiek J, Chen Q, Miller D, Shuga J, Williams S, Nemec C, Trudel G, Pelchat M, Laneuville O, De Vlaminck I, Gross S, Bolton KL, Bailey SM, Granstein R, Furman D, Melnick AM, Costes SV, Shirah B, Yu M, Menon AS, Mateus J, Mey… See abstract for full author list ➔ Overbey EG, et al. Among authors: furman d. Nature. 2024 Aug;632(8027):1145-1154. doi: 10.1038/s41586-024-07639-y. Epub 2024 Jun 11. Nature. 2024. PMID: 38862028 Free PMC article.
Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight.
Wu F, Du H, Overbey E, Kim J, Makhijani P, Martin N, Lerner CA, Nguyen K, Baechle J, Valentino TR, Fuentealba M, Bartleson JM, Halaweh H, Winer S, Meydan C, Garrett-Bakelman F, Sayed N, Melov S, Muratani M, Gerencser AA, Kasler HG, Beheshti A, Mason CE, Furman D, Winer DA. Wu F, et al. Among authors: furman d. Nat Commun. 2024 Jun 11;15(1):4795. doi: 10.1038/s41467-023-42013-y. Nat Commun. 2024. PMID: 38862487 Free PMC article.
To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants.
Corti G, Kim J, Enguita FJ, Guarnieri JW, Grossman LI, Costes SV, Fuentealba M, Scott RT, Magrini A, Sanders LM, Singh K, Sen CK, Juran CM, Paul AM, Furman D, Calleja-Agius J, Mason CE, Galeano D, Bottini M, Beheshti A. Corti G, et al. Among authors: furman d. Commun Biol. 2024 Oct 5;7(1):1268. doi: 10.1038/s42003-024-06944-6. Commun Biol. 2024. PMID: 39369042 Free PMC article.
Author Correction: To boldly go where no microRNAs have gone before: spaceflight impact on risk for small-for-gestational-age infants.
Corti G, Kim J, Enguita FJ, Guarnieri JW, Grossman LI, Costes SV, Fuentealba M, Scott RT, Magrini A, Sanders LM, Singh K, Sen CK, Juran CM, Paul AM, Furman D, Calleja-Agius J, Mason CE, Galeano D, Bottini M, Beheshti A. Corti G, et al. Among authors: furman d. Commun Biol. 2024 Oct 16;7(1):1339. doi: 10.1038/s42003-024-07022-7. Commun Biol. 2024. PMID: 39414932 Free PMC article. No abstract available.
Age-related brain atrophy is not a homogenous process: Different functional brain networks associate differentially with aging and blood factors.
Markov NT, Lindbergh CA, Staffaroni AM, Perez K, Stevens M, Nguyen K, Murad NF, Fonseca C, Campisi J, Kramer J, Furman D. Markov NT, et al. Among authors: furman d. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2207181119. doi: 10.1073/pnas.2207181119. Epub 2022 Dec 2. Proc Natl Acad Sci U S A. 2022. PMID: 36459652 Free PMC article.
Author Correction: An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging.
Sayed N, Huang Y, Nguyen K, Krejciova-Rajaniemi Z, Grawe AP, Gao T, Tibshirani R, Hastie T, Alpert A, Cui L, Kuznetsova T, Rosenberg-Hasson Y, Ostan R, Monti D, Lehallier B, Shen-Orr SS, Maecker HT, Dekker CL, Wyss-Coray T, Franceschi C, Jojic V, Haddad F, Montoya JG, Wu JC, Davis MM, Furman D. Sayed N, et al. Among authors: furman d. Nat Aging. 2021 Aug;1(8):748. doi: 10.1038/s43587-021-00102-x. Nat Aging. 2021. PMID: 37117770 No abstract available.
A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring.
Alpert A, Pickman Y, Leipold M, Rosenberg-Hasson Y, Ji X, Gaujoux R, Rabani H, Starosvetsky E, Kveler K, Schaffert S, Furman D, Caspi O, Rosenschein U, Khatri P, Dekker CL, Maecker HT, Davis MM, Shen-Orr SS. Alpert A, et al. Among authors: furman d. Nat Med. 2019 Mar;25(3):487-495. doi: 10.1038/s41591-019-0381-y. Epub 2019 Mar 6. Nat Med. 2019. PMID: 30842675 Free PMC article.
182 results