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Page 1
EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function.
Isshiki Y, Chen X, Teater M, Karagiannidis I, Nam H, Cai W, Meydan C, Xia M, Shen H, Gutierrez J, Easwar Kumar V, Carrasco SE, Ouseph MM, Yamshon S, Martin P, Griess O, Shema E, Porazzi P, Ruella M, Brentjens RJ, Inghirami G, Zappasodi R, Chadburn A, Melnick AM, Béguelin W. Isshiki Y, et al. Among authors: meydan c. Cancer Cell. 2024 Nov 30:S1535-6108(24)00441-0. doi: 10.1016/j.ccell.2024.11.006. Online ahead of print. Cancer Cell. 2024. PMID: 39642889
Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes.
Topper MJ, Guarnieri JW, Haltom JA, Chadburn A, Cope H, Frere J, An J, Borczuk A, Sinha S, Kim J, Park J, Butler D, Meydan C, Foox J, Bram Y, Richard SA, Epsi NJ, Agan B, Chenoweth JG, Simons MP, Tribble D, Burgess T, Dalgard C, Heise MT, Moorman NJ, Baxter VK, Madden EA, Taft-Benz SA, Anderson EJ, Sanders WA, Dickmander RJ, Beigel K, Widjaja GA, Janssen KA, Lie T, Murdock DG, Angelin A, Soto Albrecht YE, Olali AZ, Cen Z, Dybas J, Priebe W, Emmett MR, Best SM, Kelsey Johnson M, Trovao NS, Clark KB, Zaksas V, Meller R, Grabham P, Schisler JC, Moraes-Vieira PM, Pollett S, Mason CE, Syrkin Wurtele E, Taylor D, Schwartz RE, Beheshti A, Wallace DC, Baylin SB. Topper MJ, et al. Among authors: meydan c. Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2401968121. doi: 10.1073/pnas.2401968121. Epub 2024 Nov 27. Proc Natl Acad Sci U S A. 2024. PMID: 39602262 Free PMC article.
A Multiomics, Molecular Atlas of Breast Cancer Survivors.
Bauer BA, Schmidt CM, Ruddy KJ, Olson JE, Meydan C, Schmidt JC, Smith SY, Couch FJ, Earls JC, Price ND, Dudley JT, Mason CE, Zhang B, Phipps SM, Schmidt MA. Bauer BA, et al. Among authors: meydan c. Metabolites. 2024 Jul 20;14(7):396. doi: 10.3390/metabo14070396. Metabolites. 2024. PMID: 39057719 Free PMC article.
Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing.
Al-Turki TM, Maranon DG, Nelson CB, Lewis AM, Luxton JJ, Taylor LE, Altina N, Wu F, Du H, Kim J, Damle N, Overbey E, Meydan C, Grigorev K, Winer DA, Furman D, Mason CE, Bailey SM. Al-Turki TM, et al. Among authors: meydan c. Commun Biol. 2024 Jun 11;7(1):698. doi: 10.1038/s42003-024-06014-x. Commun Biol. 2024. PMID: 38862827 Free PMC article.
Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology.
Cope H, Elsborg J, Demharter S, McDonald JT, Wernecke C, Parthasarathy H, Unadkat H, Chatrathi M, Claudio J, Reinsch S, Avci P, Zwart SR, Smith SM, Heer M, Muratani M, Meydan C, Overbey E, Kim J, Chin CR, Park J, Schisler JC, Mason CE, Szewczyk NJ, Willis CRG, Salam A, Beheshti A. Cope H, et al. Among authors: meydan c. Commun Med (Lond). 2024 Jun 11;4(1):106. doi: 10.1038/s43856-024-00532-9. Commun Med (Lond). 2024. PMID: 38862781 Free PMC article.
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight.
Tierney BT, Kim J, Overbey EG, Ryon KA, Foox J, Sierra MA, Bhattacharya C, Damle N, Najjar D, Park J, Garcia Medina JS, Houerbi N, Meydan C, Wain Hirschberg J, Qiu J, Kleinman AS, Al-Ghalith GA, MacKay M, Afshin EE, Dhir R, Borg J, Gatt C, Brereton N, Readhead BP, Beyaz S, Venkateswaran KJ, Wiseman K, Moreno J, Boddicker AM, Zhao J, Lajoie BR, Scott RT, Altomare A, Kruglyak S, Levy S, Church GM, Mason CE. Tierney BT, et al. Among authors: meydan c. Nat Microbiol. 2024 Jul;9(7):1661-1675. doi: 10.1038/s41564-024-01635-8. Epub 2024 Jun 11. Nat Microbiol. 2024. PMID: 38862604 Free PMC article.
Aging and putative frailty biomarkers are altered by spaceflight.
Camera A, Tabetah M, Castañeda V, Kim J, Galsinh AS, Haro-Vinueza A, Salinas I, Seylani A, Arif S, Das S, Mori MA, Carano A, de Oliveira LC, Muratani M, Barker R, Zaksas V, Goel C, Dimokidis E, Taylor DM, Jeong J, Overbey E, Meydan C, Porterfield DM, Díaz JE, Caicedo A, Schisler JC, Laiakis EC, Mason CE, Kim MS, Karouia F, Szewczyk NJ, Beheshti A. Camera A, et al. Among authors: meydan c. Sci Rep. 2024 Jun 11;14(1):13098. doi: 10.1038/s41598-024-57948-5. Sci Rep. 2024. PMID: 38862573 Free PMC article.
Spatiotemporal expression and control of haemoglobin in space.
Borg J, Loy C, Kim J, Buhagiar A, Chin C, Damle N, De Vlaminck I, Felice A, Liu T, Matei I, Meydan C, Muratani M, Mzava O, Overbey E, Ryon KA, Smith SM, Tierney BT, Trudel G, Zwart SR, Beheshti A, Mason CE, Borg J. Borg J, et al. Among authors: meydan c. Nat Commun. 2024 Jun 11;15(1):4927. doi: 10.1038/s41467-024-49289-8. Nat Commun. 2024. PMID: 38862545 Free PMC article.
Space radiation damage rescued by inhibition of key spaceflight associated miRNAs.
McDonald JT, Kim J, Farmerie L, Johnson ML, Trovao NS, Arif S, Siew K, Tsoy S, Bram Y, Park J, Overbey E, Ryon K, Haltom J, Singh U, Enguita FJ, Zaksas V, Guarnieri JW, Topper M, Wallace DC, Meydan C, Baylin S, Meller R, Muratani M, Porterfield DM, Kaufman B, Mori MA, Walsh SB, Sigaudo-Roussel D, Mebarek S, Bottini M, Marquette CA, Wurtele ES, Schwartz RE, Galeano D, Mason CE, Grabham P, Beheshti A. McDonald JT, et al. Among authors: meydan c. Nat Commun. 2024 Jun 11;15(1):4825. doi: 10.1038/s41467-024-48920-y. Nat Commun. 2024. PMID: 38862542 Free PMC article.
Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight.
Kim J, Tierney BT, Overbey EG, Dantas E, Fuentealba M, Park J, Narayanan SA, Wu F, Najjar D, Chin CR, Meydan C, Loy C, Mathyk B, Klotz R, Ortiz V, Nguyen K, Ryon KA, Damle N, Houerbi N, Patras LI, Schanzer N, Hutchinson GA, Foox J, Bhattacharya C, Mackay M, Afshin EE, Hirschberg JW, Kleinman AS, Schmidt JC, Schmidt CM, Schmidt MA, Beheshti A, Matei I, Lyden D, Mullane S, Asadi A, Lenz JS, Mzava O, Yu M, Ganesan S, De Vlaminck I, Melnick AM, Barisic D, Winer DA, Zwart SR, Crucian BE, Smith SM, Mateus J, Furman D, Mason CE. Kim J, et al. Among authors: meydan c. Nat Commun. 2024 Jun 11;15(1):4954. doi: 10.1038/s41467-024-49211-2. Nat Commun. 2024. PMID: 38862516 Free PMC article.
117 results