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Page 1
IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY REVEALED BY BRAIN-METASTATIC MELANOMA MODELS.
Daugherty-Lopès A, Pérez-Guijarro E, Gopalan V, Rappaport J, Chen Q, Huang A, Lam KC, Chin S, Ebersole J, Wu E, Needle GA, Church I, Kyriakopoulos G, Xie S, Zhao Y, Gruen C, Sassano A, Araya RE, Thorkelsson A, Smith C, Lee MP, Hannenhalli S, Day CP, Merlino G, Goldszmid RS. Daugherty-Lopès A, et al. Among authors: needle ga. bioRxiv [Preprint]. 2024 Oct 9:2024.08.26.609785. doi: 10.1101/2024.08.26.609785. bioRxiv. 2024. PMID: 39372744 Free PMC article. Preprint.
Author Correction: Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Bader JE, Wolf MM, Lupica-Tondo GL, Madden MZ, Reinfeld BI, Arner EN, Hathaway ES, Steiner KK, Needle GA, Hatem Z, Landis MD, Faneuff EE, Blackman A, Wolf EM, Cottam MA, Ye X, Bates ME, Smart K, Wang W, Pinheiro LV, Christofides A, Smith D, Boussiotis VA, Haake SM, Beckermann KE, Wellen KE, Reinhart-King CA, Serezani CH, Lee CH, Aubrey C, Chen H, Rathmell WK, Hasty AH, Rathmell JC. Bader JE, et al. Among authors: needle ga. Nature. 2024 Jul;631(8022):E16. doi: 10.1038/s41586-024-07794-2. Nature. 2024. PMID: 38982216 No abstract available.
Obesity induces PD-1 on macrophages to suppress anti-tumour immunity.
Bader JE, Wolf MM, Lupica-Tondo GL, Madden MZ, Reinfeld BI, Arner EN, Hathaway ES, Steiner KK, Needle GA, Hatem Z, Landis MD, Faneuff EE, Blackman A, Wolf EM, Cottam MA, Ye X, Bates ME, Smart K, Wang W, Pinheiro LV, Christofides A, Smith D, Boussiotis VA, Haake SM, Beckermann KE, Wellen KE, Reinhart-King CA, Serezani CH, Lee CH, Aubrey C, Chen H, Rathmell WK, Hasty AH, Rathmell JC. Bader JE, et al. Among authors: needle ga. Nature. 2024 Jun;630(8018):968-975. doi: 10.1038/s41586-024-07529-3. Epub 2024 Jun 12. Nature. 2024. PMID: 38867043
Differential Effects of Glutamine Inhibition Strategies on Antitumor CD8 T Cells.
Madden MZ, Ye X, Chi C, Fisher EL, Wolf MM, Needle GA, Bader JE, Patterson AR, Reinfeld BI, Landis MD, Hathaway ES, Muka JE, O'Neil RT, Karijolich J, Philip M, Rathmell JC. Madden MZ, et al. Among authors: needle ga. J Immunol. 2023 Aug 15;211(4):563-575. doi: 10.4049/jimmunol.2200715. J Immunol. 2023. PMID: 37341499 Free PMC article.
Melanoma clonal subline analysis uncovers heterogeneity-driven immunotherapy resistance mechanisms.
Gruen C, Yang HH, Sassano A, Wu E, Gopalan V, Marie KL, Castro A, Mehrabadi FR, Wu CH, Church I, Needle GA, Smith C, Chin S, Ebersole J, Marcelus C, Fon A, Liu H, Malikic S, Sahinalp C, Carter H, Hannenhalli S, Day CP, Lee MP, Merlino G, Pérez-Guijarro E. Gruen C, et al. Among authors: needle ga. bioRxiv [Preprint]. 2023 Apr 5:2023.04.03.535074. doi: 10.1101/2023.04.03.535074. bioRxiv. 2023. PMID: 37333132 Free PMC article. Preprint.
Functional Overlap of Inborn Errors of Immunity and Metabolism Genes Define T Cell Immunometabolic Vulnerabilities.
Patterson AR, Needle GA, Sugiura A, Chi C, Steiner KK, Fisher EL, Robertson GL, Bodnya C, Markle JG, Gama V, Rathmell JC. Patterson AR, et al. Among authors: needle ga. bioRxiv [Preprint]. 2023 Jan 24:2023.01.24.525419. doi: 10.1101/2023.01.24.525419. bioRxiv. 2023. Update in: Sci Immunol. 2024 Aug 16;9(98):eadh0368. doi: 10.1126/sciimmunol.adh0368 PMID: 36747715 Free PMC article. Updated. Preprint.
Elevated transferrin receptor impairs T cell metabolism and function in systemic lupus erythematosus.
Voss K, Sewell AE, Krystofiak ES, Gibson-Corley KN, Young AC, Basham JH, Sugiura A, Arner EN, Beavers WN, Kunkle DE, Dickson ME, Needle GA, Skaar EP, Rathmell WK, Ormseth MJ, Major AS, Rathmell JC. Voss K, et al. Among authors: needle ga. Sci Immunol. 2023 Jan 13;8(79):eabq0178. doi: 10.1126/sciimmunol.abq0178. Epub 2023 Jan 13. Sci Immunol. 2023. PMID: 36638190 Free PMC article.