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Author Correction: Costimulation blockade in combination with IL-2 permits regulatory T cell sparing immunomodulation that inhibits autoimmunity.
Wang CJ, Petersone L, Edner NM, Heuts F, Ovcinnikovs V, Ntavli E, Kogimtzis A, Fabri A, Elfaki Y, Houghton LP, Hosse RJ, Schubert DA, Frei AP, Ross EM, Walker LSK. Wang CJ, et al. Among authors: edner nm. Nat Commun. 2023 Sep 15;14(1):5724. doi: 10.1038/s41467-023-41483-4. Nat Commun. 2023. PMID: 37714833 Free PMC article. No abstract available.
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation.
Petersone L, Wang CJ, Edner NM, Fabri A, Nikou SA, Hinze C, Ross EM, Ntavli E, Elfaki Y, Heuts F, Ovcinnikovs V, Rueda Gonzalez A, Houghton LP, Li HM, Zhang Y, Toellner KM, Walker LSK. Petersone L, et al. Among authors: edner nm. J Exp Med. 2023 Oct 2;220(10):e20221653. doi: 10.1084/jem.20221653. Epub 2023 Jul 19. J Exp Med. 2023. PMID: 37466652 Free PMC article.
Therapeutic gene editing of T cells to correct CTLA-4 insufficiency.
Fox TA, Houghton BC, Petersone L, Waters E, Edner NM, McKenna A, Preham O, Hinze C, Williams C, de Albuquerque AS, Kennedy A, Pesenacker AM, Genovese P, Walker LSK, Burns SO, Sansom DM, Booth C, Morris EC. Fox TA, et al. Among authors: edner nm. Sci Transl Med. 2022 Oct 26;14(668):eabn5811. doi: 10.1126/scitranslmed.abn5811. Epub 2022 Oct 26. Sci Transl Med. 2022. PMID: 36288278
Targeting co-stimulatory molecules in autoimmune disease.
Edner NM, Carlesso G, Rush JS, Walker LSK. Edner NM, et al. Nat Rev Drug Discov. 2020 Dec;19(12):860-883. doi: 10.1038/s41573-020-0081-9. Epub 2020 Sep 16. Nat Rev Drug Discov. 2020. PMID: 32939077 Review.
Follicular helper T cell profiles predict response to costimulation blockade in type 1 diabetes.
Edner NM, Heuts F, Thomas N, Wang CJ, Petersone L, Kenefeck R, Kogimtzis A, Ovcinnikovs V, Ross EM, Ntavli E, Elfaki Y, Eichmann M, Baptista R, Ambery P, Jermutus L, Peakman M, Rosenthal M, Walker LSK. Edner NM, et al. Nat Immunol. 2020 Oct;21(10):1244-1255. doi: 10.1038/s41590-020-0744-z. Epub 2020 Aug 3. Nat Immunol. 2020. PMID: 32747817 Free PMC article. Clinical Trial.
13 results