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Pharmacological reduction of coagulation factor XI reduces macrophage accumulation and accelerates deep vein thrombosis resolution in a mouse model of venous thrombosis.
Jordan KR, Wyatt CR, Fallon ME, Woltjer R, Neuwelt EA, Cheng Q, Gailani D, Lorentz C, Tucker EI, McCarty OJT, Hinds MT, Nguyen KP. Jordan KR, et al. Among authors: hinds mt. J Thromb Haemost. 2022 Sep;20(9):2035-2045. doi: 10.1111/jth.15777. Epub 2022 Jul 18. J Thromb Haemost. 2022. PMID: 35638310 Free PMC article.
Role of platelet count in a murine stasis model of deep vein thrombosis.
Mathews R, Setthavongsack N, Le-Cook A, Kaempf A, Loftis JM, Woltjer RL, Lorentz CU, Revenko A, Hinds MT, Nguyen KP. Mathews R, et al. Among authors: hinds mt. Platelets. 2024 Dec;35(1):2290916. doi: 10.1080/09537104.2023.2290916. Epub 2023 Dec 15. Platelets. 2024. PMID: 38099327 Free article.
Contact Activation Inhibitor and Factor XI Antibody, AB023, Produces Safe, Dose-Dependent Anticoagulation in a Phase 1 First-In-Human Trial.
Lorentz CU, Verbout NG, Wallisch M, Hagen MW, Shatzel JJ, Olson SR, Puy C, Hinds MT, McCarty OJT, Gailani D, Gruber A, Tucker EI. Lorentz CU, et al. Among authors: hinds mt. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):799-809. doi: 10.1161/ATVBAHA.118.312328. Arterioscler Thromb Vasc Biol. 2019. PMID: 30700130 Free PMC article. Clinical Trial.
Antibody inhibition of contact factor XII reduces platelet deposition in a model of extracorporeal membrane oxygenator perfusion in nonhuman primates.
Wallisch M, Lorentz CU, Lakshmanan HHS, Johnson J, Carris MR, Puy C, Gailani D, Hinds MT, McCarty OJT, Gruber A, Tucker EI. Wallisch M, et al. Among authors: hinds mt. Res Pract Thromb Haemost. 2020 Feb 11;4(2):205-216. doi: 10.1002/rth2.12309. eCollection 2020 Feb. Res Pract Thromb Haemost. 2020. PMID: 32110750 Free PMC article.
93 results