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Disrupting the RNA polymerase II transcription cycle through CDK7 inhibition ameliorates inflammatory arthritis.
Chen X, Shibu G, Sokolsky BA, Soussana TN, Fisher L, Deochand DK, Dacic M, Mantel I, Ramirez DC, Bell RD, Zhang T, Donlin LT, Goodman SM, Gray NS, Chinenov Y, Fisher RP, Rogatsky I. Chen X, et al. Among authors: rogatsky i. Sci Transl Med. 2024 Nov 20;16(774):eadq5091. doi: 10.1126/scitranslmed.adq5091. Epub 2024 Nov 20. Sci Transl Med. 2024. PMID: 39565872
Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity.
Delconte RB, Owyong M, Santosa EK, Srpan K, Sheppard S, McGuire TJ, Abbasi A, Diaz-Salazar C, Chun J, Rogatsky I, Hsu KC, Jordan S, Merad M, Sun JC. Delconte RB, et al. Among authors: rogatsky i. Immunity. 2024 Aug 13;57(8):1923-1938.e7. doi: 10.1016/j.immuni.2024.05.021. Epub 2024 Jun 14. Immunity. 2024. PMID: 38878769
The interferon-rich skin environment regulates Langerhans cell ADAM17 to promote photosensitivity in lupus.
Li TM, Zyulina V, Seltzer ES, Dacic M, Chinenov Y, Daamen AR, Veiga KR, Schwartz N, Oliver DJ, Cabahug-Zuckerman P, Lora J, Liu Y, Shipman WD, Ambler WG, Taber SF, Onel KB, Zippin JH, Rashighi M, Krueger JG, Anandasabapathy N, Rogatsky I, Jabbari A, Blobel CP, Lipsky PE, Lu TT. Li TM, et al. Among authors: rogatsky i. Elife. 2024 Jun 11;13:e85914. doi: 10.7554/eLife.85914. Elife. 2024. PMID: 38860651 Free PMC article.
Mechanisms of Epigenomic and Functional Convergence Between Glucocorticoid- and IL4-Driven Macrophage Programming.
Deochand DK, Dacic M, Bale MJ, Daman AW, Josefowicz SZ, Oliver D, Chinenov Y, Rogatsky I. Deochand DK, et al. Among authors: rogatsky i. bioRxiv [Preprint]. 2024 Feb 18:2024.02.16.580560. doi: 10.1101/2024.02.16.580560. bioRxiv. 2024. Update in: Nat Commun. 2024 Oct 18;15(1):9000. doi: 10.1038/s41467-024-52942-x PMID: 38405750 Free PMC article. Updated. Preprint.
Genomic glucocorticoid action in embryonic mouse neural stem cells.
Berry KJ, Chandran U, Mu F, Deochand DK, Lei T, Pagin M, Nicolis SK, Monaghan-Nichols AP, Rogatsky I, DeFranco DB. Berry KJ, et al. Among authors: rogatsky i. Mol Cell Endocrinol. 2023 Mar 1;563:111864. doi: 10.1016/j.mce.2023.111864. Epub 2023 Jan 20. Mol Cell Endocrinol. 2023. PMID: 36690169 Free PMC article.
55 results