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The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA.
Watanabe A, Koyano F, Imai K, Hizukuri Y, Ogiwara S, Ito T, Miyamoto J, Shibuya C, Kimura M, Toriumi K, Motono C, Arai M, Tanaka K, Akiyama Y, Yamano K, Matsuda N. Watanabe A, et al. Among authors: tanaka k. J Biol Chem. 2024 Jul;300(7):107476. doi: 10.1016/j.jbc.2024.107476. Epub 2024 Jun 13. J Biol Chem. 2024. PMID: 38879013 Free PMC article.
AAA+ ATPase chaperone p97/VCPFAF2 governs basal pexophagy.
Koyano F, Yamano K, Hoshina T, Kosako H, Fujiki Y, Tanaka K, Matsuda N. Koyano F, et al. Among authors: tanaka k. Nat Commun. 2024 Oct 29;15(1):9347. doi: 10.1038/s41467-024-53558-x. Nat Commun. 2024. PMID: 39472561 Free PMC article.
WEE1 Confers Resistance to KRASG12C Inhibitors in Non-Small Cell Lung Cancer.
Yamamoto G, Tanaka K, Kamata R, Saito H, Yamamori-Morita T, Nakao T, Liu J, Mori S, Yagishita S, Hamada A, Shinno Y, Yoshida T, Horinouchi H, Ohe Y, Watanabe SI, Yatabe Y, Kitai H, Konno S, Kobayashi SS, Ohashi A. Yamamoto G, et al. Among authors: tanaka k. Cancer Lett. 2024 Dec 24:217414. doi: 10.1016/j.canlet.2024.217414. Online ahead of print. Cancer Lett. 2024. PMID: 39725152
Dual single‑nucleotide polymorphism biomarker combination for opioid selection to treat cancer pain.
Fujita Y, Matsuoka H, Chiba Y, Tsurutani J, Yoshida T, Sakai K, Nakura M, Sakamoto R, Makimura C, Ohtake Y, Tanaka K, Hayashi H, Takahama T, Tanizaki J, Koyama A, Nishio K, Nakagawa K. Fujita Y, et al. Among authors: tanaka k. Mol Clin Oncol. 2024 Nov 29;22(2):14. doi: 10.3892/mco.2024.2809. eCollection 2025 Feb. Mol Clin Oncol. 2024. PMID: 39720462 Free PMC article.
Chemical biology tools take the strain.
Vong K, Tanaka K. Vong K, et al. Among authors: tanaka k. Nat Chem Biol. 2025 Jan;21(1):24-26. doi: 10.1038/s41589-024-01780-5. Nat Chem Biol. 2025. PMID: 39719490 No abstract available.
A conserved human CD4+ T cell subset recognizing the mycobacterial adjuvant, trehalose monomycolate.
Sakai Y, Asa M, Hirose M, Kusuhara W, Fujiwara N, Tamashima H, Ikazaki T, Oka S, Kuraba K, Tanaka K, Yoshiyama T, Nagae M, Hoshino Y, Motooka D, Van Rhijn I, Lu X, Ishikawa E, Moody DB, Kato T, Inuki S, Hirai G, Yamasaki S. Sakai Y, et al. Among authors: tanaka k. J Clin Invest. 2024 Dec 24:e185443. doi: 10.1172/JCI185443. Online ahead of print. J Clin Invest. 2024. PMID: 39718834 Free article.
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