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Enhancing pediatric access to cell and gene therapies.
Mackall CL, Bollard CM, Goodman N, Carr C, Gardner R, Rouce R, Sotillo E, Stoner R, Urnov FD, Wayne AS, Park J, Kohn DB. Mackall CL, et al. Among authors: gardner r. Nat Med. 2024 Jul;30(7):1836-1846. doi: 10.1038/s41591-024-03035-1. Epub 2024 Jun 17. Nat Med. 2024. PMID: 38886624 Review.
ACT To Sustain: Adoptive Cell Therapy To Sustain Access to Non-Commercialized Genetically Modified Cell Therapies.
Gardner RA, White C, Elsallab M, Farnia S, Fraint E, Grilley B, Bateman-House A, Grupp SA, Kenderian S, Locke FL, Nikiforow S, Oluwole OO, Rouce RH, Spiegel J, Shah NN, Sharma A, Komanduri K, Gill S. Gardner RA, et al. Transplant Cell Ther. 2024 Aug;30(8):776-787. doi: 10.1016/j.jtct.2024.05.010. Epub 2024 May 16. Transplant Cell Ther. 2024. PMID: 38762057 Review.
Modified Manufacturing Process Modulates CD19CAR T-cell Engraftment Fitness and Leukemia-Free Survival in Pediatric and Young Adult Subjects.
Ceppi F, Wilson AL, Annesley C, Kimmerly GR, Summers C, Brand A, Seidel K, Wu QV, Beebe A, Brown C, Mgebroff S, Lindgren C, Rawlings-Rhea SD, Huang W, Pulsipher MA, Wayne AS, Park JR, Jensen MC, Gardner RA. Ceppi F, et al. Among authors: gardner ra. Cancer Immunol Res. 2022 Jul 1;10(7):856-870. doi: 10.1158/2326-6066.CIR-21-0501. Cancer Immunol Res. 2022. PMID: 35580141 Free PMC article. Clinical Trial.
Treatment-related adverse events associated with a modified UK ALLR3 induction chemotherapy backbone for childhood relapsed/refractory acute lymphoblastic leukemia.
Sun W, Orgel E, Malvar J, Sposto R, Wilkes JJ, Gardner R, Tolbert VP, Smith A, Hur M, Hoffman J, Rheingold SR, Burke MJ, Wayne AS. Sun W, et al. Among authors: gardner r. Pediatr Blood Cancer. 2016 Nov;63(11):1943-8. doi: 10.1002/pbc.26129. Epub 2016 Jul 20. Pediatr Blood Cancer. 2016. PMID: 27437864 Free PMC article.
Development of a Safety Surveillance Plan for the Academic Medicine Sponsor Performing First-in-Human Cellular Therapy Clinical Trials: A Report from the Consortium for Pediatric Cellular Immunotherapy.
Adams C, Keller M, Michlitsch JG, Aguayo-Hiraldo P, Chen K, Hossain MZ, Davis A, Park JR, Verneris MR, Gardner RA. Adams C, et al. Among authors: gardner ra. Transplant Cell Ther. 2024 May;30(5):475-487. doi: 10.1016/j.jtct.2024.02.022. Epub 2024 Mar 4. Transplant Cell Ther. 2024. PMID: 38447751 Review.
Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study.
Burke MJ, Kostadinov R, Sposto R, Gore L, Kelley SM, Rabik C, Trepel JB, Lee MJ, Yuno A, Lee S, Bhojwani D, Jeha S, Chang BH, Sulis ML, Hermiston ML, Gaynon P, Huynh V, Verma A, Gardner R, Heym KM, Dennis RM, Ziegler DS, Laetsch TW, Oesterheld JE, Dubois SG, Pollard JA, Glade-Bender J, Cooper TM, Kaplan JA, Farooqi MS, Yoo B, Guest E, Wayne AS, Brown PA. Burke MJ, et al. Among authors: gardner r. Clin Cancer Res. 2020 May 15;26(10):2297-2307. doi: 10.1158/1078-0432.CCR-19-1251. Epub 2020 Jan 22. Clin Cancer Res. 2020. PMID: 31969338 Free PMC article. Clinical Trial.
Outcome of children with multiply relapsed B-cell acute lymphoblastic leukemia: a therapeutic advances in childhood leukemia & lymphoma study.
Sun W, Malvar J, Sposto R, Verma A, Wilkes JJ, Dennis R, Heym K, Laetsch TW, Widener M, Rheingold SR, Oesterheld J, Hijiya N, Sulis ML, Huynh V, Place AE, Bittencourt H, Hutchinson R, Messinger Y, Chang B, Matloub Y, Ziegler DS, Gardner R, Cooper T, Ceppi F, Hermiston M, Dalla-Pozza L, Schultz KR, Gaynon P, Wayne AS, Whitlock JA. Sun W, et al. Among authors: gardner r. Leukemia. 2018 Nov;32(11):2316-2325. doi: 10.1038/s41375-018-0094-0. Epub 2018 Mar 15. Leukemia. 2018. PMID: 29728694 Free PMC article.
Paving the Road for Chimeric Antigen Receptor T Cells: American Society for Transplantation and Cellular Therapy 80/20 Task Force Consensus on Challenges and Solutions to Improving Efficiency of Clinical Center Certification and Maintenance of Operations for Commercially Approved Immune Effector Cell Therapies.
Nikiforow S, Frigault MJ, Frey NV, Gardner RA, Komanduri KV, Perales MA, Kebriaei P, Warkentin PI, Pasquini M, Aho JL, Levine BL, Heslop HE, Hlucky TL, Habucky K, Gharibo M, Jagasia M, Locke FL. Nikiforow S, et al. Transplant Cell Ther. 2023 Apr;29(4):228-239. doi: 10.1016/j.jtct.2023.01.021. Epub 2023 Jan 26. Transplant Cell Ther. 2023. PMID: 36709800 Free article.
CAR T cells for other pediatric non-B-cell hematologic malignancies.
Lamble AJ, Gardner R. Lamble AJ, et al. Among authors: gardner r. Hematology Am Soc Hematol Educ Program. 2020 Dec 4;2020(1):494-500. doi: 10.1182/hematology.2020000134. Hematology Am Soc Hematol Educ Program. 2020. PMID: 33275678 Free PMC article. Review.
2,259 results